Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds

A nonlinear dynamical system, in which the feed rates of glycerol and alkali are taken as the control functions, is first proposed to formulate the fed-batch culture of 1,3-propanediol (1,3-PD) production. To maximize the 1,3-PD concentration at the terminal time, a constrained optimal control model...

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Main Authors: Chongyang Liu, Zhaohua Gong, Zhaoyi Huo, Bangyu Shen
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Applied Mathematics
Online Access:http://dx.doi.org/10.1155/2012/245315
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author Chongyang Liu
Zhaohua Gong
Zhaoyi Huo
Bangyu Shen
author_facet Chongyang Liu
Zhaohua Gong
Zhaoyi Huo
Bangyu Shen
author_sort Chongyang Liu
collection DOAJ
description A nonlinear dynamical system, in which the feed rates of glycerol and alkali are taken as the control functions, is first proposed to formulate the fed-batch culture of 1,3-propanediol (1,3-PD) production. To maximize the 1,3-PD concentration at the terminal time, a constrained optimal control model is then presented. A solution approach is developed to seek the optimal feed rates based on control vector parametrization method and improved differential evolution algorithm. The proposed methodology yielded an increase by 32.17% of 1,3-PD concentration at the terminal time.
format Article
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institution Kabale University
issn 1110-757X
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language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Journal of Applied Mathematics
spelling doaj-art-16e67e43111f4dc4bab5ac2dafb51f582025-08-20T03:54:33ZengWileyJournal of Applied Mathematics1110-757X1687-00422012-01-01201210.1155/2012/245315245315Optimal Control of a Fed-Batch Fermentation Involving Multiple FeedsChongyang Liu0Zhaohua Gong1Zhaoyi Huo2Bangyu Shen3School of Mathematics and Information Science, Shandong Institute of Business and Technology, Yantai 264005, Shandong, ChinaSchool of Mathematics and Information Science, Shandong Institute of Business and Technology, Yantai 264005, Shandong, ChinaSchool of Energy and Power Engineering, Dalian University of Technology, Dalian, Liaoning 116024, ChinaSchool of Mathematical Science, Huaiyin Normal University, Huai'an 223300, Jiangsu, ChinaA nonlinear dynamical system, in which the feed rates of glycerol and alkali are taken as the control functions, is first proposed to formulate the fed-batch culture of 1,3-propanediol (1,3-PD) production. To maximize the 1,3-PD concentration at the terminal time, a constrained optimal control model is then presented. A solution approach is developed to seek the optimal feed rates based on control vector parametrization method and improved differential evolution algorithm. The proposed methodology yielded an increase by 32.17% of 1,3-PD concentration at the terminal time.http://dx.doi.org/10.1155/2012/245315
spellingShingle Chongyang Liu
Zhaohua Gong
Zhaoyi Huo
Bangyu Shen
Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
Journal of Applied Mathematics
title Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
title_full Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
title_fullStr Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
title_full_unstemmed Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
title_short Optimal Control of a Fed-Batch Fermentation Involving Multiple Feeds
title_sort optimal control of a fed batch fermentation involving multiple feeds
url http://dx.doi.org/10.1155/2012/245315
work_keys_str_mv AT chongyangliu optimalcontrolofafedbatchfermentationinvolvingmultiplefeeds
AT zhaohuagong optimalcontrolofafedbatchfermentationinvolvingmultiplefeeds
AT zhaoyihuo optimalcontrolofafedbatchfermentationinvolvingmultiplefeeds
AT bangyushen optimalcontrolofafedbatchfermentationinvolvingmultiplefeeds