Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse. [version 2; peer review: 2 approved]

Case Report: Genetic evolution of Burkholderia pseudomallei during treatment leading to antibiotic resistance and disease relapse. [version 2; peer review: 2 approved]

Background Melioidosis is a significant yet neglected cause of sepsis in tropical regions, particularly in southeast Asia, with poor clinical outcomes. It is a growing threat with an expanding global footprint. The causative organism, Burkholderia pseudomallei, is intrinsically resistant to most fir...

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Main Authors: Ko Chang, Elizabeth A. Ashley, Claire Chewapreecha, Anousone Douangnouvong, Chantisa Keeratipusana, Terry John Evans, Koukeo Phommasone, Davanh Sengdatka, Elizabeth M. Batty, Vilayouth Phimolsarnnousith
Format: Article
Language:English
Published: Wellcome 2025-07-01
Series:Wellcome Open Research
Subjects:
Burkholderia pseudomallei
melioidosis
Lao PDR
southeast Asia
sepsis
antimicrobial resistance
eng
Online Access:https://wellcomeopenresearch.org/articles/10-281/v2
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