The effect of baseline versus early glucocorticoid use on immune checkpoint inhibitor efficacy in patients with advanced NSCLC

The effect of baseline versus early glucocorticoid use on immune checkpoint inhibitor efficacy in patients with advanced NSCLC

PurposeThis study aims to investigate the specific effects of glucocorticoids (GC) on the efficacy of immune checkpoint inhibitors (ICIs), and whether this effect is influenced by the timing and dosage of GC administration. Changes in the neutrophil percentage and the helper/suppressor T lymphocyte...

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Bibliographic Details
Main Authors: Yifan Wang, Jianying Zhou, Simin Peng, Zhao Cui, Weiqi Wang, Wenqin Zeng, Tingting Qiu, Zhentian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
glucocorticoids
immune checkpoint inhibitors
efficacy
timing of use
NEUT%/(CD4+/CD8+)
non-small cell lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1533556/full
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