DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA
Acute lymphoblastic leukemia (ALL) is a disseminated malignancy of B- or T-lymphoblasts which imposes a rapid and accurate diagnostic process to support an optimal risk-oriented therapy and thus increase the curability rate. The need for a precise diagnostic algorithm is underlined by the awareness...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2014-10-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/2095 |
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| _version_ | 1846095147745411072 |
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| author | Sabina Chiaretti Gina Zini Renato Bassan |
| author_facet | Sabina Chiaretti Gina Zini Renato Bassan |
| author_sort | Sabina Chiaretti |
| collection | DOAJ |
| description | Acute lymphoblastic leukemia (ALL) is a disseminated malignancy of B- or T-lymphoblasts which imposes a rapid and accurate diagnostic process to support an optimal risk-oriented therapy and thus increase the curability rate. The need for a precise diagnostic algorithm is underlined by the awareness that both ALL therapy and related success rates may vary greatly in function of ALL subset, from standard chemotherapy in patients with standard-risk ALL, to allotransplantation (SCT) and targeted therapy in high-risk patients and cases expressing suitable biological targets, respectively. This review offers a glimpse on how best identify ALL and the most relevant ALL subsets. |
| format | Article |
| id | doaj-art-1650f0e2f1ad4d1585d95e0631c6e91b |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-10-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-1650f0e2f1ad4d1585d95e0631c6e91b2025-01-02T11:34:03ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-10-0161e2014073e201407310.4084/mjhid.2014.0731530DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIASabina ChiarettiGina ZiniRenato BassanAcute lymphoblastic leukemia (ALL) is a disseminated malignancy of B- or T-lymphoblasts which imposes a rapid and accurate diagnostic process to support an optimal risk-oriented therapy and thus increase the curability rate. The need for a precise diagnostic algorithm is underlined by the awareness that both ALL therapy and related success rates may vary greatly in function of ALL subset, from standard chemotherapy in patients with standard-risk ALL, to allotransplantation (SCT) and targeted therapy in high-risk patients and cases expressing suitable biological targets, respectively. This review offers a glimpse on how best identify ALL and the most relevant ALL subsets.http://www.mjhid.org/index.php/mjhid/article/view/2095Acute Lymphoid LeukemiaALL classification |
| spellingShingle | Sabina Chiaretti Gina Zini Renato Bassan DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA Mediterranean Journal of Hematology and Infectious Diseases Acute Lymphoid Leukemia ALL classification |
| title | DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA |
| title_full | DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA |
| title_fullStr | DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA |
| title_full_unstemmed | DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA |
| title_short | DIAGNOSIS AND SUBCLASSIFICATION OF ACUTE LYMPHOBLASTIC LEUKEMIA |
| title_sort | diagnosis and subclassification of acute lymphoblastic leukemia |
| topic | Acute Lymphoid Leukemia ALL classification |
| url | http://www.mjhid.org/index.php/mjhid/article/view/2095 |
| work_keys_str_mv | AT sabinachiaretti diagnosisandsubclassificationofacutelymphoblasticleukemia AT ginazini diagnosisandsubclassificationofacutelymphoblasticleukemia AT renatobassan diagnosisandsubclassificationofacutelymphoblasticleukemia |