Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13

Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13

Abstract Background Sepsis is a systemic inflammatory response caused by infection. When this inflammatory response spreads to the lungs, it can lead to acute lung injury (ALI) or more severe acute respiratory distress syndrome (ARDS). Pulmonary fibrosis is a potential complication of these conditio...

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Bibliographic Details
Main Authors: Cheng Tan, Hang Zhou, Qiangfei Xiong, Xian Xian, Qiyuan Liu, Zexin Zhang, Jingjing Xu, Hao Yao
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Respiratory Research
Subjects:
LPS
Pulmonary fibrosis
Mast cell
IL-13
Cromolyn sodium
Sepsis
Online Access:https://doi.org/10.1186/s12931-024-03045-0
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