Protection of tooth structure by chlorhexidine and natural polyphenols: a review

Caries is a multifactorial and transmittable disease that results mainly from bacteria present in the oral cavity. Oral microorganisms can produce metabolic acids that diffuse through dental tissues and interfaces leading to dissolution of mineral. In dentine, after mineral is dissolved, organic ma...

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Main Authors: Vinay Pilly, Carlos Henrique Lacerda Brito Junior, Getulio Rocha Nogueira Filho, Anuradha Prakki
Format: Article
Language:English
Published: Universidade Estadual Paulista 2012-12-01
Series:Brazilian Dental Science
Online Access:https://ojs.ict.unesp.br/index.php/cob/article/view/838
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author Vinay Pilly
Carlos Henrique Lacerda Brito Junior
Getulio Rocha Nogueira Filho
Anuradha Prakki
author_facet Vinay Pilly
Carlos Henrique Lacerda Brito Junior
Getulio Rocha Nogueira Filho
Anuradha Prakki
author_sort Vinay Pilly
collection DOAJ
description Caries is a multifactorial and transmittable disease that results mainly from bacteria present in the oral cavity. Oral microorganisms can produce metabolic acids that diffuse through dental tissues and interfaces leading to dissolution of mineral. In dentine, after mineral is dissolved, organic matrix is also exposed to breakdown by host enzymes such as matrix metalloproteinases (MMPs) that are activated by low pH followed by neutralization. This review aims to discuss the activity of different antibacterial and antiproteolytic compounds such as chlorhexidine and natural polyphenols in the control of caries progression. Keywords: chlorhexidine, catechin, polyphenol, caries, dentine
format Article
id doaj-art-15e8a8e16ecc4d10a2d1c8b867fc5ca0
institution Kabale University
issn 2178-6011
language English
publishDate 2012-12-01
publisher Universidade Estadual Paulista
record_format Article
series Brazilian Dental Science
spelling doaj-art-15e8a8e16ecc4d10a2d1c8b867fc5ca02025-08-22T17:56:24ZengUniversidade Estadual PaulistaBrazilian Dental Science2178-60112012-12-0115410.14295/bds.2012.v15i4.838Protection of tooth structure by chlorhexidine and natural polyphenols: a reviewVinay Pilly0Carlos Henrique Lacerda Brito Junior1Getulio Rocha Nogueira Filho2Anuradha Prakki3University of TorontoUniversity of TorontoUniversity of TorontoUniversity of Toronto Caries is a multifactorial and transmittable disease that results mainly from bacteria present in the oral cavity. Oral microorganisms can produce metabolic acids that diffuse through dental tissues and interfaces leading to dissolution of mineral. In dentine, after mineral is dissolved, organic matrix is also exposed to breakdown by host enzymes such as matrix metalloproteinases (MMPs) that are activated by low pH followed by neutralization. This review aims to discuss the activity of different antibacterial and antiproteolytic compounds such as chlorhexidine and natural polyphenols in the control of caries progression. Keywords: chlorhexidine, catechin, polyphenol, caries, dentine https://ojs.ict.unesp.br/index.php/cob/article/view/838
spellingShingle Vinay Pilly
Carlos Henrique Lacerda Brito Junior
Getulio Rocha Nogueira Filho
Anuradha Prakki
Protection of tooth structure by chlorhexidine and natural polyphenols: a review
Brazilian Dental Science
title Protection of tooth structure by chlorhexidine and natural polyphenols: a review
title_full Protection of tooth structure by chlorhexidine and natural polyphenols: a review
title_fullStr Protection of tooth structure by chlorhexidine and natural polyphenols: a review
title_full_unstemmed Protection of tooth structure by chlorhexidine and natural polyphenols: a review
title_short Protection of tooth structure by chlorhexidine and natural polyphenols: a review
title_sort protection of tooth structure by chlorhexidine and natural polyphenols a review
url https://ojs.ict.unesp.br/index.php/cob/article/view/838
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