Decreased neuronal excitability in hypertriglyceridemia hamsters with acute seizures

Decreased neuronal excitability in hypertriglyceridemia hamsters with acute seizures

IntroductionNeonatal seizures are the most common clinical manifestation of neurological dysfunction in newborns, with an incidence ranging from 1 to 5‰. However, the therapeutic efficacy of current pharmacological treatments remains suboptimal. This study aims to utilize genetically modified hamste...

Full description

Saved in:

Bibliographic Details
Main Authors:	Qiuyue Shen, Nana Liu, Yuwu Jiang, Lili Liu, Xinlin Hou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Neurology
Subjects:	seizure hypertriglyceridemia ZDHHC14 transient outward K+ currents palmitoylation modification
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2024.1500737/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

ZDHHC20 mediated S-palmitoylation of fatty acid synthase (FASN) promotes hepatocarcinogenesis
by: Yaqi Mo, et al.
Published: (2024-12-01)

Expression of palmitoyl transferases in brain structures of mice genetically predisposed to depressive-like behavior
by: E. M. Kondaurova, et al.
Published: (2018-08-01)

Development of a hamster model of spontaneous hypertriglyceridemia in diabetes
by: Ya‐Hong Ma, et al.
Published: (2024-12-01)

Hypertriglyceridemia-induced pancreatitis in pregnancy and its management issues: A case-based study
by: Babul Reddy Hanmayyagari, et al.
Published: (2020-01-01)

Severe hypertriglyceridemia in an adolescent female with diabetic ketoacidosis: A case report
by: Noopur N. Kulkarni, et al.
Published: (2024-09-01)

Rare presentation of vitamin D toxicity with hypertriglyceridemia and pancreatitis
by: Bushra Rehman, et al.
Published: (2025-01-01)

Can severe hypertriglyceridemia cause angina in the absence of significant coronary artery lesions?
by: Mustafa Zain, et al.
Published: (2024-11-01)

Evaluation and Management of Patients with Seizures in the Emergency Department: A One-Year Analysis
by: K. Puteikis, et al.
Published: (2018-09-01)

Triglyceride-lowering therapies in hypertriglyceridemia-associated acute pancreatitis in China: a multicentre prospective cohort study
by: Jing Zhou, et al.
Published: (2024-11-01)

Usefulness of pemafibrate for non-alcoholic fatty liver disease with hypertriglyceridemia
by: Masahiro Kikuchi, et al.
Published: (2024-09-01)

VAEEG: Variational auto-encoder for extracting EEG representation
by: Tong Zhao, et al.
Published: (2024-12-01)

Association between serum hypertriglyceridemia and hematological indices: data mining approaches
by: Somayeh Ghiasi Hafezi, et al.
Published: (2024-12-01)

Unmasking a Rare Genetic Mutation: The Importance of Genetic Testing in Refractory Hypertriglyceridemia
by: Panagiotis Theodoropoulos, MD, et al.
Published: (2024-11-01)

Effectiveness and safety of anti-seizure medications for refractory partial-onset seizures based on network Meta-analysis
by: ZHANG Chao, et al.
Published: (2024-11-01)

S-palmitoylation of MAP kinase is essential for fungal virulence
by: Yuhang Duan, et al.
Published: (2024-12-01)

YOLO-IRS: Infrared Ship Detection Algorithm Based on Self-Attention Mechanism and KAN in Complex Marine Background
by: Limin Guo, et al.
Published: (2024-12-01)

Correlation between serum SUMO1 level and hypertriglyceridemia in type 2 diabetes mellitus patients
by: ZHANG Xinyan, et al.
Published: (2024-10-01)

Risk factors of seizure and complex seizure in febrile children: a clinical study
by: Farhad Heydarian, et al.
Published: (2024-11-01)

Genetic and biochemical analysis of severe hypertriglyceridemia complicated with acute pancreatitis or with low post-heparin lipoprotein lipase mass
by: Takashi Suzuki, et al.
Published: (2024-05-01)

Value of the systemic immunoinflammatory index, nutritional risk index, and triglyceride-glucose index in predicting the condition and prognosis of patients with hypertriglyceridemia-associated acute pancreatitis
by: Yuan Zhen Wang, et al.
Published: (2025-01-01)

Palmitic Acid Accelerates Endothelial Cell Injury and Cardiovascular Dysfunction via Palmitoylation of PKM2
by: Yu He, et al.
Published: (2025-02-01)

Protein S-palmitoylation regulates the virulence of plant pathogenic fungi
by: Mengmeng Guo, et al.
Published: (2025-02-01)

The effects of pulse amplitude in electroconvulsive therapy on seizure threshold, seizure duration, and time to reorientation
by: Maya Hazimeh, et al.
Published: (2025-03-01)

Analysis of Tidal Cycle Wave Breaking Distribution Characteristics on a Low-Tide Terrace Beach Using Video Imagery Segmentation
by: Hang Yin, et al.
Published: (2024-12-01)

Timing Mechanisms for Circadian Seizures
by: Kristina Slabeva, et al.
Published: (2024-10-01)

SEEG-Based Bilateral Seizure Network Analysis for Neurostimulation Treatment
by: Genchang Peng, et al.
Published: (2025-01-01)

Hyponatremia with an Osmolar Gap, Pseudohyponatremia or Hyper-Osmolar Hyponatremia?
by: Leonardo Pozo Garcia, et al.
Published: (2025-06-01)

Bexarotene-induced hypothyroidism and dyslipidemia; a nation-wide study
by: Katsunori Manaka, et al.
Published: (2024-08-01)

Motivations for Outward FDI from Emerging Economies to Advanced Economies: A Literature Review
by: Ibrahim Nandom Yakubu, et al.
Published: (2020-06-01)

Seizure prophylaxis in pneumococcal meningitis, cohort study
by: Lluïsa Guillem, et al.
Published: (2024-12-01)

Takotsubo cardiomyopathy triggered by frequent psychogenic nonepileptic seizures: A case report
by: Daichi Yomogida, et al.
Published: (2024-01-01)

Seizure in geriatric population – An unheeded integer
by: Namitha Narayanan, et al.
Published: (2023-04-01)

Association between seizure susceptibility with type and optimal dose of antihistamine in patients with a febrile seizure; A retrospective cohort study in Gorgan, Iran
by: Hossein Gorzin, et al.
Published: (2024-06-01)

Seizure Onset Zone Detection Based on Convolutional Neural Networks and EEG Signals
by: Zhejun Kuang, et al.
Published: (2024-10-01)

Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus
by: Alberto Pauletti, et al.
Published: (2025-01-01)

Incidence and predictors of seizure-related injuries among epileptic patients undergoing follow-up treatment at public hospitals in Central Ethiopia
by: Selamawit Wondale Begizew, et al.
Published: (2025-01-01)

Hypertriglyceridemic waist phenotype in older adults: prevalence and associated factors
by: Yuri Silva de Souza, et al.
Published: (2024-12-01)

Loss of PIKfyve drives the spongiform degeneration in prion diseases
by: Asvin K K Lakkaraju, et al.
Published: (2021-07-01)

A Study on Room Outward Views and Configuration and their Relation with Workers’ Spatial Satisfaction (the Case of Tehran District 1 Municipality Building)
by: Mohammad Reza Namdari, et al.
Published: (2017-09-01)

Influence of sleep on seizures and interictal epileptiform discharges in epilepsy
by: Jun-Sang Sunwoo
Published: (2025-01-01)