HiFiBGC: an ensemble approach for improved biosynthetic gene cluster detection in PacBio HiFi-read metagenomes

Abstract Background Microbes produce diverse bioactive natural products with applications in fields such as medicine and agriculture. In their genomes, these natural products are encoded by physically clustered genes known as biosynthetic gene clusters (BGCs). Genome and metagenome sequencing advanc...

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Bibliographic Details
Main Authors: Amit Yadav, Srikrishna Subramanian
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-024-10950-7
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