Novel benzoylurea derivative decreases TRPM7 channel function and inhibits cancer cells migration

The transient receptor potential melastatin 7 channel (TRPM7) is a nonselective cation channel highly expressed in some human cancer tissues. TRPM7 is involved in the proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) of cancer cells. Modulation of TRPM7 could be a promi...

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Bibliographic Details
Main Authors: Xiaoding Zhang, Rui Zong, Yu Han, Xiaoming Li, Shuangyu Liu, Yixue Cao, Nan Jiang, Pingping Chen, Haixia Gao
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Channels
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19336950.2024.2396339
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