Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study
Background Urinary tract infection (UTI) is a common Emergency Department (ED) diagnosis and cause of hospitalization. This study aimed to assess the incidence of UTI-related referrals and admissions in the Region of Southern Denmark and describe patient demographics, clinical and laboratory finding...
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Taylor & Francis Group
2025-12-01
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| Series: | Annals of Medicine |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2025.2546059 |
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| author | Ida Christine Schütt Gustav Emil Hansen Alexander Koch-Pedersen Annmarie Lassen Flemming Schønning Rosenvinge Christian Backer Mogensen Helene Skjøt-Arkil Lone Wulff Madsen Isik Somuncu Johansen |
| author_facet | Ida Christine Schütt Gustav Emil Hansen Alexander Koch-Pedersen Annmarie Lassen Flemming Schønning Rosenvinge Christian Backer Mogensen Helene Skjøt-Arkil Lone Wulff Madsen Isik Somuncu Johansen |
| author_sort | Ida Christine Schütt |
| collection | DOAJ |
| description | Background Urinary tract infection (UTI) is a common Emergency Department (ED) diagnosis and cause of hospitalization. This study aimed to assess the incidence of UTI-related referrals and admissions in the Region of Southern Denmark and describe patient demographics, clinical and laboratory findings, readmission rates and mortality.Materials and methods This retrospective cohort study included all referrals to five EDs in the Region of Southern Denmark from January 1, 2016, to March 19, 2018. Patients aged ≥18 years, with a UTI discharge diagnosis were included.Results A total of 3,754 individual UTI patients were identified, corresponding to an incidence of 17.6 per 10,000 person-years and an admission rate of 10.8 per 10,000 person-years. Admitted patients were older (median age: 77 years), had more comorbidities, higher CRP and leukocyte levels (p < .001). E. coli was the most frequent pathogen in both urine (66.6%) and blood cultures (53.6%). Admission was associated with male sex (OR 1.32), age 60–80 years (OR 3.07), ≥81 (OR 3.60), Charlson Comorbidity Index (CCI) ≥3 (OR 1.34), qSOFA = 1 (OR 1.56), and initiation of antibiotic treatment (OR 4.08). Thirty-day mortality was 7.4%, with age ≥81 (OR 3.86), CCI ≥3 (OR 2.73), and qSOFA = 3 (OR 5.49) as significant risk factors. Among patients who were not admitted at the initial contact, 5.1% required hospitalization within 30 days.Conclusions UTIs are a common cause of hospitalization and represent a substantial healthcare burden in Denmark. Older age, male sex, comorbidities, and severe clinical presentations were key predictors of admission and mortality. |
| format | Article |
| id | doaj-art-1517d5ea6de04f45a9ffe6d7d971dd2a |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-1517d5ea6de04f45a9ffe6d7d971dd2a2025-08-20T03:44:13ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2546059Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort studyIda Christine Schütt0Gustav Emil Hansen1Alexander Koch-Pedersen2Annmarie Lassen3Flemming Schønning Rosenvinge4Christian Backer Mogensen5Helene Skjøt-Arkil6Lone Wulff Madsen7Isik Somuncu Johansen8Department of Infectious Diseases, Odense University Hospital, Odense, DenmarkDepartment of Infectious Diseases, Odense University Hospital, Odense, DenmarkDepartment of Infectious Diseases, Odense University Hospital, Odense, DenmarkDepartment of Emergency Medicine, Odense University Hospital, Odense, DenmarkDepartment of Clinical Microbiology, Odense University Hospital, Odense, DenmarkDepartment of Emergency Medicine, University Hospital of Southern Denmark, Aabenraa, DenmarkDepartment of Emergency Medicine, University Hospital of Southern Denmark, Aabenraa, DenmarkDepartment of Infectious Diseases, Odense University Hospital, Odense, DenmarkDepartment of Infectious Diseases, Odense University Hospital, Odense, DenmarkBackground Urinary tract infection (UTI) is a common Emergency Department (ED) diagnosis and cause of hospitalization. This study aimed to assess the incidence of UTI-related referrals and admissions in the Region of Southern Denmark and describe patient demographics, clinical and laboratory findings, readmission rates and mortality.Materials and methods This retrospective cohort study included all referrals to five EDs in the Region of Southern Denmark from January 1, 2016, to March 19, 2018. Patients aged ≥18 years, with a UTI discharge diagnosis were included.Results A total of 3,754 individual UTI patients were identified, corresponding to an incidence of 17.6 per 10,000 person-years and an admission rate of 10.8 per 10,000 person-years. Admitted patients were older (median age: 77 years), had more comorbidities, higher CRP and leukocyte levels (p < .001). E. coli was the most frequent pathogen in both urine (66.6%) and blood cultures (53.6%). Admission was associated with male sex (OR 1.32), age 60–80 years (OR 3.07), ≥81 (OR 3.60), Charlson Comorbidity Index (CCI) ≥3 (OR 1.34), qSOFA = 1 (OR 1.56), and initiation of antibiotic treatment (OR 4.08). Thirty-day mortality was 7.4%, with age ≥81 (OR 3.86), CCI ≥3 (OR 2.73), and qSOFA = 3 (OR 5.49) as significant risk factors. Among patients who were not admitted at the initial contact, 5.1% required hospitalization within 30 days.Conclusions UTIs are a common cause of hospitalization and represent a substantial healthcare burden in Denmark. Older age, male sex, comorbidities, and severe clinical presentations were key predictors of admission and mortality.https://www.tandfonline.com/doi/10.1080/07853890.2025.2546059AdmissionincidenceoutcomeUTIurinary tract infection |
| spellingShingle | Ida Christine Schütt Gustav Emil Hansen Alexander Koch-Pedersen Annmarie Lassen Flemming Schønning Rosenvinge Christian Backer Mogensen Helene Skjøt-Arkil Lone Wulff Madsen Isik Somuncu Johansen Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study Annals of Medicine Admission incidence outcome UTI urinary tract infection |
| title | Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study |
| title_full | Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study |
| title_fullStr | Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study |
| title_full_unstemmed | Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study |
| title_short | Incidence and outcomes of patients admitted to emergency departments with urinary tract infections in Denmark: a retrospective cohort study |
| title_sort | incidence and outcomes of patients admitted to emergency departments with urinary tract infections in denmark a retrospective cohort study |
| topic | Admission incidence outcome UTI urinary tract infection |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2025.2546059 |
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