Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia.

Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia.

Production of melanin pigments is a protective mechanism of the skin against ultraviolet (UV)-induced damage and carcinogenesis. However, the molecular basis for melanogenesis is still poorly understood. Herein, we demonstrate a critical interplay between the primary cilium and the melanocortin 1 re...

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Main Authors: Xiaoyu Tian, Hanyu Wang, Song Liu, Wei Liu, Kaiyue Zhang, Xiaohan Gao, Qingchao Li, Huijie Zhao, Liangran Zhang, Peiwei Liu, Min Liu, Youjun Wang, Xueliang Zhu, Rutao Cui, Jun Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002940
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