The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia
Objective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records in...
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| Format: | Article |
| Language: | English |
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Universitas Andalas
2024-05-01
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| Series: | Majalah Kedokteran Andalas |
| Online Access: | https://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1527 |
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| author | Ika Kurnia Febrianti Andani Eka Putra Raveinal Raveinal Aisyah Elliyanti |
| author_facet | Ika Kurnia Febrianti Andani Eka Putra Raveinal Raveinal Aisyah Elliyanti |
| author_sort | Ika Kurnia Febrianti |
| collection | DOAJ |
| description | Objective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records including demographic data, and laboratory results such as hemoglobin, hematocrit, leukocytes, platelets, coagulation markers (D-dimer, PT, and APTT), and patients outcomes post-treatment. Statistical analysis is performed by using chi-square and Mann-Whitney tests were considered statistically difference level of significant between variables. Result: The COVID-19 patients is classified into mild group with 27 subjects (44.2%) and moderate-severe group 34 subjects (55.8%). Leukocytes, D-dimer, and PT levels significantly differed between mild and moderate-severe groups. All coagulation markers had a symptomatic effect on Covid-19 patients, increased D-dimer and prolonged prothrombin time in adult COVID-19 patients tend to be followed by the enhancement of severe symptoms and death |
| format | Article |
| id | doaj-art-14a08e0860fc477f82d38205473de730 |
| institution | Kabale University |
| issn | 0126-2092 2442-5230 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Universitas Andalas |
| record_format | Article |
| series | Majalah Kedokteran Andalas |
| spelling | doaj-art-14a08e0860fc477f82d38205473de7302024-11-12T02:06:22ZengUniversitas AndalasMajalah Kedokteran Andalas0126-20922442-52302024-05-0146101712172310.25077/mka.v46.i10.p1712-1723.2024859The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, IndonesiaIka Kurnia Febrianti0Andani Eka PutraRaveinal RaveinalAisyah ElliyantiDoctoral Program Biomedical Science, Faculty of Medicine, Andalas University, Padang, Indonesia/ Department of Medical Laboratory Technology, STIKES Syedza Saintika, Padang, IndonesiaObjective: This study aimed to determine the description of the coagulation marker and how it implicates COVID-19 patients based on clinical outcomes in the form of enhancement severity and death. Method: The subjects were collected from patients with positive COVID-19 RT-PCR with medical records including demographic data, and laboratory results such as hemoglobin, hematocrit, leukocytes, platelets, coagulation markers (D-dimer, PT, and APTT), and patients outcomes post-treatment. Statistical analysis is performed by using chi-square and Mann-Whitney tests were considered statistically difference level of significant between variables. Result: The COVID-19 patients is classified into mild group with 27 subjects (44.2%) and moderate-severe group 34 subjects (55.8%). Leukocytes, D-dimer, and PT levels significantly differed between mild and moderate-severe groups. All coagulation markers had a symptomatic effect on Covid-19 patients, increased D-dimer and prolonged prothrombin time in adult COVID-19 patients tend to be followed by the enhancement of severe symptoms and deathhttps://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1527 |
| spellingShingle | Ika Kurnia Febrianti Andani Eka Putra Raveinal Raveinal Aisyah Elliyanti The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia Majalah Kedokteran Andalas |
| title | The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia |
| title_full | The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia |
| title_fullStr | The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia |
| title_full_unstemmed | The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia |
| title_short | The Enhancement of COVID-19 Severity on Coagulation Markers: a Cross-sectional Study in West Sumatra, Indonesia |
| title_sort | enhancement of covid 19 severity on coagulation markers a cross sectional study in west sumatra indonesia |
| url | https://jurnalmka.fk.unand.ac.id/index.php/art/article/view/1527 |
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