Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients
Aim. Using twin models, to demonstrate the leading role of environmental factors for blood pressure (BP) variability (Var) and circadian rhythm (CR) parameters. Material and methods. In total, 74 twin pairs with normal BP (mean age 42,4±2,3 years) and 64 twin pairs with arterial hypertension (AH) (m...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2007-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1138 |
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| author | A. P. Sharandak L. L. Kirichenko Zh. Yu. Dvoryanchikova O. S. Tseka A. P. Korolev M. V. Koroleva E. T. Lilyin |
| author_facet | A. P. Sharandak L. L. Kirichenko Zh. Yu. Dvoryanchikova O. S. Tseka A. P. Korolev M. V. Koroleva E. T. Lilyin |
| author_sort | A. P. Sharandak |
| collection | DOAJ |
| description | Aim. Using twin models, to demonstrate the leading role of environmental factors for blood pressure (BP) variability (Var) and circadian rhythm (CR) parameters. Material and methods. In total, 74 twin pairs with normal BP (mean age 42,4±2,3 years) and 64 twin pairs with arterial hypertension (AH) (mean age 52,76±3,2 years) were examined. Simultaneous pair-wise 24-hour BP monitoring (BPM) was performed with АВРМ-02 device (“MEDITECH”, Hungary). Var of mean systolic BP (VMSBP), mean diastolic BP (DBP), mean hemodynamic BP (VMBP) and mean pulse BP (VPBP) was investigated, as well as Var of mean heart rate (HR) and circadian indices (CI) for SBP, DPB and MBP. Results. In participants with normal BP, environmental factors played the leading role in forming BP Var parameters. In AH patients, hereditary factors input in daytime VPBP was about 21%. Nighttime VSBP and VMBP were genotype-influenced by 22% and 36%, respectively. Random environmental factors were more influential for CIin AH patients; in AH-free individuals, environmental and hereditary factors were equally influential. Conclusion. Random and systematic environmental factors play a leading role in forming BP Var and CR in AH twins, with minimal role of hereditary factors. |
| format | Article |
| id | doaj-art-146d3d06614d4171b4768a390566b27b |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2007-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-146d3d06614d4171b4768a390566b27b2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252007-02-01612327850Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patientsA. P. Sharandak0L. L. Kirichenko1Zh. Yu. Dvoryanchikova2O. S. Tseka3A. P. Korolev4M. V. Koroleva5E. T. Lilyin6Moscow State Medico-Stomatological UniversityMoscow State Medico-Stomatological UniversityMoscow State Medico-Stomatological UniversityClinical Hospital No 85, «Medbioextrem», MoscowClinical Hospital No 85, «Medbioextrem», MoscowMoscow State Medico-Stomatological UniversityClinical Hospital No 85, «Medbioextrem», MoscowAim. Using twin models, to demonstrate the leading role of environmental factors for blood pressure (BP) variability (Var) and circadian rhythm (CR) parameters. Material and methods. In total, 74 twin pairs with normal BP (mean age 42,4±2,3 years) and 64 twin pairs with arterial hypertension (AH) (mean age 52,76±3,2 years) were examined. Simultaneous pair-wise 24-hour BP monitoring (BPM) was performed with АВРМ-02 device (“MEDITECH”, Hungary). Var of mean systolic BP (VMSBP), mean diastolic BP (DBP), mean hemodynamic BP (VMBP) and mean pulse BP (VPBP) was investigated, as well as Var of mean heart rate (HR) and circadian indices (CI) for SBP, DPB and MBP. Results. In participants with normal BP, environmental factors played the leading role in forming BP Var parameters. In AH patients, hereditary factors input in daytime VPBP was about 21%. Nighttime VSBP and VMBP were genotype-influenced by 22% and 36%, respectively. Random environmental factors were more influential for CIin AH patients; in AH-free individuals, environmental and hereditary factors were equally influential. Conclusion. Random and systematic environmental factors play a leading role in forming BP Var and CR in AH twins, with minimal role of hereditary factors.https://cardiovascular.elpub.ru/jour/article/view/1138arterial hypertensionblood pressure variabilitycircadian indextwin methodheredityenvironment |
| spellingShingle | A. P. Sharandak L. L. Kirichenko Zh. Yu. Dvoryanchikova O. S. Tseka A. P. Korolev M. V. Koroleva E. T. Lilyin Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients Кардиоваскулярная терапия и профилактика arterial hypertension blood pressure variability circadian index twin method heredity environment |
| title | Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients |
| title_full | Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients |
| title_fullStr | Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients |
| title_full_unstemmed | Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients |
| title_short | Environmental factors’ influence on blood pressure variability and circadian rhythm in arterial hypertension patients |
| title_sort | environmental factors influence on blood pressure variability and circadian rhythm in arterial hypertension patients |
| topic | arterial hypertension blood pressure variability circadian index twin method heredity environment |
| url | https://cardiovascular.elpub.ru/jour/article/view/1138 |
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