Alterations of gut microbiota and metabolome are associated with primary nephrotic syndrome in children

Alterations of gut microbiota and metabolome are associated with primary nephrotic syndrome in children

Abstract Background Primary nephrotic syndrome (PNS) is a common glomerular disease in children. Dysbiosis of gut microbiota acts as a cause of Treg abnormalities. However, the intestinal metabolic impact of PNS with children remains poorly understood. This study aims to investigate the dynamic chan...

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Main Authors: Xiaolong Ma, Ting Li, Chunxia Liu, Huiqing Ge, Dandan Zheng, Junbai Ma, Yamei Guo, Xiaoxu Zhang, Jian Liu, Yuanyuan Liu, Yiwei Li, Wenke Shen, Yunyun Ma, Yajuan Liu, Rong Su, Ting Wang, Xiaoxia Zhang, Jinhai Ma, Hao Wang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Microbiology
Subjects:
PNS
Immune inflammation
Treg/Th17
Gut microbiota
Metabolome
Faecalibacterium
Online Access:https://doi.org/10.1186/s12866-024-03667-w
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https://doi.org/10.1186/s12866-024-03667-w

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