The potential mechanism of Saikosaponin D against luminal A breast cancer based on bioinformatical analysis, molecular docking and in vitro studies

The potential mechanism of Saikosaponin D against luminal A breast cancer based on bioinformatical analysis, molecular docking and in vitro studies

Abstract Background Saikosaponin D (SSD) has been shown to have the strongest anti-tumor activity. This study aimed to explore the effects and potential molecular mechanism of Saikosaponin D (SSD) against estrogen receptor-positive breast cancer. Methods MCF-7 and T-47D cell lines were treated with...

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Bibliographic Details
Main Authors: Lichang Yang, Ru Chang, Jianzhen Pan, Shan Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Hereditas
Subjects:
Estrogen receptor
Breast cancer
Saikosaponin D
Proliferation
Cell cycle
Online Access:https://doi.org/10.1186/s41065-025-00510-8
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