General Phenotype of NADase Induction by CLI Treatment in Streptococcus pyogenes
The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic-shock syndrome (STSS). However, we previously reported that a “subinhibitory dose” of CLI induced the expression of the NAD-glycohydrolase (NADase) exotoxin in an emm1-type...
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Main Authors: | Ichiro Tatsuno, Masanori Isaka, Tadao Hasegawa |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | International Journal of Microbiology |
Online Access: | http://dx.doi.org/10.1155/2022/4767765 |
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