Quorum-Sensing inhibition by furanone compounds and therapeutic effects on Pseudomonas aeruginosa keratitis rabbit model

Quorum-Sensing inhibition by furanone compounds and therapeutic effects on Pseudomonas aeruginosa keratitis rabbit model

Abstract Background To investigate Quorum-Sensing inhibition by furanone compounds in Pseudomonas aeruginosa keratitis rabbit model. Methods Thirty adult New Zealand White rabbits were used. Anesthetized rabbits were intrastromally injected with Pseudomonas aeruginosa (P. aeruginosa). The rabbits we...

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Bibliographic Details
Main Authors: Aleyna Dal, Rümeysa Hekimoğlu, Bilge Sümbül, Fatmanur Babalı Balıbey, Zeynep Özman Gökçe, Ersin Akbulut, Ahmet Elbay
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Ophthalmology
Subjects:
Furanone
Keratitis
Pseudomonas aeruginosa
Quorum-Sensing
Online Access:https://doi.org/10.1186/s12886-025-04061-4
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