The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine

Objective: The development of ion-releasing resin composites is expected to reduce the risk of secondary caries. This study compared the degree of monomer conversion, biaxial flexural strength/modulus, elemental release, and remineralisation potential of a novel ion-releasing dental composite (Rene...

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Main Authors: Munchuporn Pariwatanasak, Saowapa Chadarat, Wisitsin Potiprapanpong, Sukanya Kyopun, Anne M. Young, Piyaphong Panpisut
Format: Article
Language:English
Published: Medical Journals Sweden 2025-08-01
Series:Biomaterial Investigations in Dentistry
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Online Access:https://medicaljournalssweden.se/biid/article/view/44551
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author Munchuporn Pariwatanasak
Saowapa Chadarat
Wisitsin Potiprapanpong
Sukanya Kyopun
Anne M. Young
Piyaphong Panpisut
author_facet Munchuporn Pariwatanasak
Saowapa Chadarat
Wisitsin Potiprapanpong
Sukanya Kyopun
Anne M. Young
Piyaphong Panpisut
author_sort Munchuporn Pariwatanasak
collection DOAJ
description Objective: The development of ion-releasing resin composites is expected to reduce the risk of secondary caries. This study compared the degree of monomer conversion, biaxial flexural strength/modulus, elemental release, and remineralisation potential of a novel ion-releasing dental composite (Renewal MI) containing monocalcium phosphate monohydrate and polylysine.  Materials and methods: The degree of monomer conversion after light curing for 20 s was determined (n = 8). The biaxial flexural strength and modulus after immersion in water for 24 h (n = 8) were evaluated. Additionally, the release of Ca and P after immersion in water for 2 weeks was assessed (n = 3). A disc specimen of the material (n = 1) was attached to the demineralised dentine and then immersed in simulated body fluid for 2 weeks to qualitatively determine mineral precipitation on dentine. The commercial comparison included Filtek Z350 XT, EQUIA Forte HT, FUJI VII, and FUJI II LC. Results: FUJI II LC demonstrated the highest degree of conversion (97.6%) compared to Renewal MI (57.2%) and Filtek Z350 XT (61.2%). The highest flexural strength was observed in Filtek Z350 XT (271 MPa), followed by MI (135 MPa), FUJI II LC (109 MPa), EQUIA Forte HT (50 MPa), and FUJI VII (35 MPa). The biaxial flexural modulus of Renewal MI (3.2 GPa) was comparable to that of EQUIA FORTE HT (3.8 GPa) and FUJI II LC (3.6 GPa). Ca and P release of MI (11 ppm, 45 ppm) was higher than that of FUJI VII (<0.1 ppm, 0.7 ppm). The precipitation of mineral precipitates in dentinal tubules of demineralised dentine was not detected in all materials.  Conclusion: Renewal MI demonstrated a degree of conversion similar to commercial resin composite but exhibited lower strength. However, its strength was much higher than conventional glass ionomer cements. The material promoted the high release of elements, which was expected to encourage the remineralising actions.
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series Biomaterial Investigations in Dentistry
spelling doaj-art-13d57c5c91fe45a9a42be230b4c91c6d2025-08-20T07:05:21ZengMedical Journals SwedenBiomaterial Investigations in Dentistry2641-52752025-08-0112110.2340/biid.v12.44551The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysineMunchuporn Pariwatanasak0Saowapa Chadarat1Wisitsin Potiprapanpong2Sukanya Kyopun3Anne M. Young4Piyaphong Panpisut5Faculty of Dentistry, Thammasat University, Pathum Thani, ThailandFaculty of Dentistry, Thammasat University, Pathum Thani, ThailandFaculty of Dentistry, Thammasat University, Pathum Thani, ThailandDepartment of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, Royal Free Hospital, Rowland Hill Street, London, UK; School of Dentistry, Mae Fah Luang University, Chiang Rai, ThailandDepartment of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, Royal Free Hospital, Rowland Hill Street, London, UKFaculty of Dentistry, Thammasat University, Pathum Thani, Thailand; Thammasat University Research Unit in Dental and Bone Substitute Biomaterials, Thammasat University, Pathum Thani, Thailand Objective: The development of ion-releasing resin composites is expected to reduce the risk of secondary caries. This study compared the degree of monomer conversion, biaxial flexural strength/modulus, elemental release, and remineralisation potential of a novel ion-releasing dental composite (Renewal MI) containing monocalcium phosphate monohydrate and polylysine.  Materials and methods: The degree of monomer conversion after light curing for 20 s was determined (n = 8). The biaxial flexural strength and modulus after immersion in water for 24 h (n = 8) were evaluated. Additionally, the release of Ca and P after immersion in water for 2 weeks was assessed (n = 3). A disc specimen of the material (n = 1) was attached to the demineralised dentine and then immersed in simulated body fluid for 2 weeks to qualitatively determine mineral precipitation on dentine. The commercial comparison included Filtek Z350 XT, EQUIA Forte HT, FUJI VII, and FUJI II LC. Results: FUJI II LC demonstrated the highest degree of conversion (97.6%) compared to Renewal MI (57.2%) and Filtek Z350 XT (61.2%). The highest flexural strength was observed in Filtek Z350 XT (271 MPa), followed by MI (135 MPa), FUJI II LC (109 MPa), EQUIA Forte HT (50 MPa), and FUJI VII (35 MPa). The biaxial flexural modulus of Renewal MI (3.2 GPa) was comparable to that of EQUIA FORTE HT (3.8 GPa) and FUJI II LC (3.6 GPa). Ca and P release of MI (11 ppm, 45 ppm) was higher than that of FUJI VII (<0.1 ppm, 0.7 ppm). The precipitation of mineral precipitates in dentinal tubules of demineralised dentine was not detected in all materials.  Conclusion: Renewal MI demonstrated a degree of conversion similar to commercial resin composite but exhibited lower strength. However, its strength was much higher than conventional glass ionomer cements. The material promoted the high release of elements, which was expected to encourage the remineralising actions. https://medicaljournalssweden.se/biid/article/view/44551Resin compositebiaxial flexural strengthmonocalcium phosphate monohydratepolylysinedegree of monomer conversionremineralisation
spellingShingle Munchuporn Pariwatanasak
Saowapa Chadarat
Wisitsin Potiprapanpong
Sukanya Kyopun
Anne M. Young
Piyaphong Panpisut
The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
Biomaterial Investigations in Dentistry
Resin composite
biaxial flexural strength
monocalcium phosphate monohydrate
polylysine
degree of monomer conversion
remineralisation
title The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
title_full The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
title_fullStr The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
title_full_unstemmed The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
title_short The in vitro assessment of the degree of monomer conversion, biaxial flexural strength, and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
title_sort in vitro assessment of the degree of monomer conversion biaxial flexural strength and mineral precipitation on demineralised dentine of novel resin composite containing monocalcium phosphate monohydrate and polylysine
topic Resin composite
biaxial flexural strength
monocalcium phosphate monohydrate
polylysine
degree of monomer conversion
remineralisation
url https://medicaljournalssweden.se/biid/article/view/44551
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