Antiinflammatory and analgesic action of polar lipids of maral antlers and peat in experimental inflammation
In experimental acute exudative inflammation, caused by Difco agar injection in mice hind leg, lipids derived from maral antlers and peat decreased the leg inflammatory edema and prolonged the pain reaction latent period; in analogous model in rats prevented the edema progression. In model of prolif...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Siberian State Medical University (Tomsk)
2012-12-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/847 |
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| Summary: | In experimental acute exudative inflammation, caused by Difco agar injection in mice hind leg, lipids derived from maral antlers and peat decreased the leg inflammatory edema and prolonged the pain reaction latent period; in analogous model in rats prevented the edema progression. In model of proliferative inflammation lipids reduced granulomatous-fibrotic tissue expansion. In adjuvant arthritis maral anthlers and peat lipids suppressed the edema development of leg in which inflammatory agent was inoculated also of intact leg and had analgesic action. Maral anthlers and peat lipids diminished pain reaction also due the resorbtive action. Maral anthlers and peat lipids in effective doses 30 and 60 mg/kg had the antiinflammatory and analgesic action to the same extent as diclofenac in dose 10 mg/kg. |
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| ISSN: | 1682-0363 1819-3684 |