Evaluation of serum samples in long cryopreservation for SomaScan proteomics and sex differences in elderly Japanese adults

Evaluation of serum samples in long cryopreservation for SomaScan proteomics and sex differences in elderly Japanese adults

Abstract Many biobanks store biological samples and use them for various analyses, including proteomics. Therefore, it is necessary to consider the denaturation of target proteins during long-term storage. We analyzed 16-year-old cryopreserved serum samples using the SomaScan platform, a novel prote...

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Bibliographic Details
Main Authors:	Ruriha Beppo, Yuki Ohashi, Ken Yamamoto, Fumie Kinoshita, Tomoko S. Kato, Masahisa Katsuno, Tatsuaki Matsubara, Mitsuhiro Yokota, Sahoko Ichihara, Masahiro Nakatochi
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Series:	Scientific Reports
Subjects:	SomaScan Proteomics Gonadotropin Adiponectin Resistin
Online Access:	https://doi.org/10.1038/s41598-025-14464-4
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