The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves
Abstract Epithelioid sarcomas are rare soft tissue tumors and have possibility to involve the peripheral nerve and present as sensory and motor disorders. The symptoms are similar to those of nerve compression diseases. This situation is extremely rare in clinic and was only reported as several case...
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Nature Portfolio
2024-12-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-82357-z |
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| author | Xiaotian Jia Chaoqun Yang Lin Chen Cong Yu Tadashi Kondo |
| author_facet | Xiaotian Jia Chaoqun Yang Lin Chen Cong Yu Tadashi Kondo |
| author_sort | Xiaotian Jia |
| collection | DOAJ |
| description | Abstract Epithelioid sarcomas are rare soft tissue tumors and have possibility to involve the peripheral nerve and present as sensory and motor disorders. The symptoms are similar to those of nerve compression diseases. This situation is extremely rare in clinic and was only reported as several case reports in literature. It can be easily ignored and misdiagnosed in clinic and may bring out severe outcomes. From January 2003 to December 2017, a retrospective analysis of ten patients with epithelioid sarcomas which involved the peripheral nerves was made. The medical data, detailed clinical courses and the follow-up results were stated. In these cases, the tumors invaded the median nerve, ulnar nerve, radial nerve, brachial plexus, sciatic nerve and presented as relative symptoms. Early diagnosis and treatment are the keys to better prognosis. We recommended high-resolution ultrasound as a standard diagnostic tool for nerve compression syndromes not only reveal the morphological structure of the peripheral nerve, but also discover the tumor involving the nerve. Adequate surgical methods including wide resection and lymph node dissection if necessary. The manners of functional reconstruction need to be applied flexibly by the doctors. Postoperative rehabilitation is important for functional recovery. We want to share our experiences in the diagnosis and treatment to overcome this particular condition. |
| format | Article |
| id | doaj-art-1385c1b90d174e358cd7b2e9fc365890 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-1385c1b90d174e358cd7b2e9fc3658902024-12-29T12:18:21ZengNature PortfolioScientific Reports2045-23222024-12-011411910.1038/s41598-024-82357-zThe diagnosis and treatment of the epithelioid sarcomas involving the peripheral nervesXiaotian Jia0Chaoqun Yang1Lin Chen2Cong Yu3Tadashi Kondo4Department of Hand Surgery, Huashan Hospital, Fudan UniversityDepartment of Hand Surgery, Huashan Hospital, Fudan UniversityDepartment of Hand Surgery, Huashan Hospital, Fudan UniversityDepartment of Hand Surgery, Huashan Hospital, Fudan UniversityDivision of Rare Cancer Research, National Cancer Center Research InstituteAbstract Epithelioid sarcomas are rare soft tissue tumors and have possibility to involve the peripheral nerve and present as sensory and motor disorders. The symptoms are similar to those of nerve compression diseases. This situation is extremely rare in clinic and was only reported as several case reports in literature. It can be easily ignored and misdiagnosed in clinic and may bring out severe outcomes. From January 2003 to December 2017, a retrospective analysis of ten patients with epithelioid sarcomas which involved the peripheral nerves was made. The medical data, detailed clinical courses and the follow-up results were stated. In these cases, the tumors invaded the median nerve, ulnar nerve, radial nerve, brachial plexus, sciatic nerve and presented as relative symptoms. Early diagnosis and treatment are the keys to better prognosis. We recommended high-resolution ultrasound as a standard diagnostic tool for nerve compression syndromes not only reveal the morphological structure of the peripheral nerve, but also discover the tumor involving the nerve. Adequate surgical methods including wide resection and lymph node dissection if necessary. The manners of functional reconstruction need to be applied flexibly by the doctors. Postoperative rehabilitation is important for functional recovery. We want to share our experiences in the diagnosis and treatment to overcome this particular condition.https://doi.org/10.1038/s41598-024-82357-zEpithelioid sarcomaPeripheral nerveMisdiagnosisNerve compression diseasesHigh-resolution ultrasoundFunctional reconstruction |
| spellingShingle | Xiaotian Jia Chaoqun Yang Lin Chen Cong Yu Tadashi Kondo The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves Scientific Reports Epithelioid sarcoma Peripheral nerve Misdiagnosis Nerve compression diseases High-resolution ultrasound Functional reconstruction |
| title | The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves |
| title_full | The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves |
| title_fullStr | The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves |
| title_full_unstemmed | The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves |
| title_short | The diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves |
| title_sort | diagnosis and treatment of the epithelioid sarcomas involving the peripheral nerves |
| topic | Epithelioid sarcoma Peripheral nerve Misdiagnosis Nerve compression diseases High-resolution ultrasound Functional reconstruction |
| url | https://doi.org/10.1038/s41598-024-82357-z |
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