Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.

The aim of our study was to investigate the effectiveness of combined therapy with antiplatelet agent clopidogrel (Plagril®, “Dr. Reddy’sLaboratories Limited”, India), and lipid-lowering agent atorvastatin (Atocor®, “Dr. Reddy’s Laboratories Limited”, India) in the treatment of the miners with ische...

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Main Authors: V. I. Fesenko, V. A. Роtabashniy
Format: Article
Language:English
Published: Dnipro State Medical University 2016-03-01
Series:Medičnì Perspektivi
Subjects:
Online Access:http://journals.uran.ua/index.php/2307-0404/article/view/63472
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author V. I. Fesenko
V. A. Роtabashniy
author_facet V. I. Fesenko
V. A. Роtabashniy
author_sort V. I. Fesenko
collection DOAJ
description The aim of our study was to investigate the effectiveness of combined therapy with antiplatelet agent clopidogrel (Plagril®, “Dr. Reddy’sLaboratories Limited”, India), and lipid-lowering agent atorvastatin (Atocor®, “Dr. Reddy’s Laboratories Limited”, India) in the treatment of the miners with ischemic heart disease. A total of 30 miners have been under study. Complete physical examination, blood and urine tests, blood biochemistry, serum parameters of hemostasis, electrocardiogram, echocardiography, 24-hour ECG monitoring were performed. The treatment period was 3 months. It was established, that statin therapy with “Atocor” in combination with antiplatelet agent “Plagril” was well tolerated. The combination of medications significantly improves the clinical status of patients with coronary artery disease, along with effective correction of dyslipidemia without a negative impact on plasma hemostasis.
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institution Kabale University
issn 2307-0404
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publishDate 2016-03-01
publisher Dnipro State Medical University
record_format Article
series Medičnì Perspektivi
spelling doaj-art-1311ab3f62314a83b4b2f8fb7360a8dc2024-12-02T01:10:21ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042016-03-01211465110.26641/2307-0404.2016.1.6347263472Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.V. I. FesenkoV. A. РоtabashniyThe aim of our study was to investigate the effectiveness of combined therapy with antiplatelet agent clopidogrel (Plagril®, “Dr. Reddy’sLaboratories Limited”, India), and lipid-lowering agent atorvastatin (Atocor®, “Dr. Reddy’s Laboratories Limited”, India) in the treatment of the miners with ischemic heart disease. A total of 30 miners have been under study. Complete physical examination, blood and urine tests, blood biochemistry, serum parameters of hemostasis, electrocardiogram, echocardiography, 24-hour ECG monitoring were performed. The treatment period was 3 months. It was established, that statin therapy with “Atocor” in combination with antiplatelet agent “Plagril” was well tolerated. The combination of medications significantly improves the clinical status of patients with coronary artery disease, along with effective correction of dyslipidemia without a negative impact on plasma hemostasis.http://journals.uran.ua/index.php/2307-0404/article/view/63472ischemic heart diseasesilent ischemialipid metabolismplasma hemostasisminers
spellingShingle V. I. Fesenko
V. A. Роtabashniy
Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.
Medičnì Perspektivi
ischemic heart disease
silent ischemia
lipid metabolism
plasma hemostasis
miners
title Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.
title_full Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.
title_fullStr Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.
title_full_unstemmed Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.
title_short Influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry.
title_sort influence of a complex tratment on serum lipid profile and clinical course of ischemic heart disease in workers of mining industry
topic ischemic heart disease
silent ischemia
lipid metabolism
plasma hemostasis
miners
url http://journals.uran.ua/index.php/2307-0404/article/view/63472
work_keys_str_mv AT vifesenko influenceofacomplextratmentonserumlipidprofileandclinicalcourseofischemicheartdiseaseinworkersofminingindustry
AT varotabashniy influenceofacomplextratmentonserumlipidprofileandclinicalcourseofischemicheartdiseaseinworkersofminingindustry