Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico

This work describes the characterization of <i>Trichoderma atroviride</i> strain CMU-08, isolated from Michoacán, Mexico. CMU-08 demonstrated robust growth and conidiation across a temperature range from 16 to 32 °C and a pH range from 4 to 9 on potato dextrose agar (PDA) and malt extrac...

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Main Authors: Karla Ivonne González-Martínez, Ma. Soledad Vázquez-Garcidueñas, Alfredo Herrera-Estrella, Sylvia P. Fernández-Pavía, Rafael Salgado-Garciglia, John Larsen, Salvador Ochoa-Ascencio, Gerardo Rodríguez-Alvarado, Gerardo Vázquez-Marrufo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Journal of Fungi
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Online Access:https://www.mdpi.com/2309-608X/10/11/758
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author Karla Ivonne González-Martínez
Ma. Soledad Vázquez-Garcidueñas
Alfredo Herrera-Estrella
Sylvia P. Fernández-Pavía
Rafael Salgado-Garciglia
John Larsen
Salvador Ochoa-Ascencio
Gerardo Rodríguez-Alvarado
Gerardo Vázquez-Marrufo
author_facet Karla Ivonne González-Martínez
Ma. Soledad Vázquez-Garcidueñas
Alfredo Herrera-Estrella
Sylvia P. Fernández-Pavía
Rafael Salgado-Garciglia
John Larsen
Salvador Ochoa-Ascencio
Gerardo Rodríguez-Alvarado
Gerardo Vázquez-Marrufo
author_sort Karla Ivonne González-Martínez
collection DOAJ
description This work describes the characterization of <i>Trichoderma atroviride</i> strain CMU-08, isolated from Michoacán, Mexico. CMU-08 demonstrated robust growth and conidiation across a temperature range from 16 to 32 °C and a pH range from 4 to 9 on potato dextrose agar (PDA) and malt extract agar (MEA) media. The strain is an efficient antagonist of six species of phytopathogenic fungi and oomycetes in PDA, MEA, and Vogel minimal medium (VMM). Antagonist mechanisms of CMU-08 included direct mycoparasitism observed in dual-culture assays, as well as antibiosis attributed to growth inhibition via both volatile and non-volatile metabolites, with the effectiveness varying depending on the test phytopathogen and culture medium. Extracellular filtrates (ECFs) recovered from liquid cultures of CMU-08 under basal and induced conditions using <i>Botrytis cinerea</i> cell walls significantly inhibited their growth at a concentration of 750 µg/mL. Moreover, in detached tomato leaf assays, these ECFs reduced foliar damage caused by <i>B. cinerea</i> by 24–34%. The volatile organic compounds (VOCs) produced by CMU-08 also exhibited substantial efficacy, reducing foliar damage by up to 50% in similar tests. Despite showing no basal extracellular chitinase enzymatic activity, CMU-08 demonstrated significant induction of this activity in cultures supplemented with <i>B. cinerea</i> and <i>Fusarium</i> sp. cell walls. Four genes encoding extracellular chitinases (<i>chit33</i>, <i>chit36</i>, <i>ech42</i>, and locus 217415) showed different dynamics of transcriptional regulation during the dual-culture confrontation of strain CMU-08 with <i>B. cinerea</i> and <i>Fusarium</i> sp., varying according to the phytopathogen and the interaction stage. The CMU-08 strain shows physiological versatility and employs a variety of antagonist mechanisms toward different species of phytopathogenic microorganisms, making it a good candidate for developing a biocontrol product for field application.
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spelling doaj-art-12fa9de156244dcea9d4c722ebdbdb4f2024-11-26T18:08:45ZengMDPI AGJournal of Fungi2309-608X2024-11-01101175810.3390/jof10110758Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central MexicoKarla Ivonne González-Martínez0Ma. Soledad Vázquez-Garcidueñas1Alfredo Herrera-Estrella2Sylvia P. Fernández-Pavía3Rafael Salgado-Garciglia4John Larsen5Salvador Ochoa-Ascencio6Gerardo Rodríguez-Alvarado7Gerardo Vázquez-Marrufo8Multidisciplinary Center for Biotechnology Studies, Faculty of Veterinary Medicine and Zootechnics, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Col. La Palma, Tarímbaro CP 58893, Michoacán, MexicoDivision of Graduate Studies, Faculty of Medical and Biological Sciences “Dr. Ignacio Chávez”, Universidad Michoacana de San Nicolás de Hidalgo, Ave. Rafael Carrillo esq. Dr. Salvador González Herrejón, Col. Cuauhtémoc, Morelia CP 58020, Michoacán, MexicoUnidad de Genómica Avanzada-Langebio, Centro de Investigación y de Estudios Avanzados del IPN, Libramiento Norte Carretera Irapuato-León km 9.6, Irapuato CP 36824, Guanajuato, MexicoInstitute of Research in Agricultural and Forestry Sciences, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Col. La Palma, Tarímbaro CP 58893, Michoacán, MexicoChemical Biological Research Institute, Universidad Michoacana de San Nicolás de Hidalgo, Av. Universidad s/n, Ciudad Universitaria, Morelia CP 58069, Michoacán, MexicoEcosystem and Sustainability Research Institute, Universidad Nacional Autónoma de México, Antigua Carretera a Pátzcuaro No.8701, Col. Ex Hacienda de San José de la Huerta, Morelia CP 58190, Michoacán, MexicoFaculty of Agrobiology, Universidad Michoacana de San Nicolás de Hidalgo, Paseo Lázaro Cárdenas 2290, Emiliano Zapata, Melchor Ocampo, Uruapan CP 60170, Michoacán, MexicoInstitute of Research in Agricultural and Forestry Sciences, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Col. La Palma, Tarímbaro CP 58893, Michoacán, MexicoMultidisciplinary Center for Biotechnology Studies, Faculty of Veterinary Medicine and Zootechnics, Universidad Michoacana de San Nicolás de Hidalgo, Km 9.5 Carretera Morelia-Zinapécuaro, Col. La Palma, Tarímbaro CP 58893, Michoacán, MexicoThis work describes the characterization of <i>Trichoderma atroviride</i> strain CMU-08, isolated from Michoacán, Mexico. CMU-08 demonstrated robust growth and conidiation across a temperature range from 16 to 32 °C and a pH range from 4 to 9 on potato dextrose agar (PDA) and malt extract agar (MEA) media. The strain is an efficient antagonist of six species of phytopathogenic fungi and oomycetes in PDA, MEA, and Vogel minimal medium (VMM). Antagonist mechanisms of CMU-08 included direct mycoparasitism observed in dual-culture assays, as well as antibiosis attributed to growth inhibition via both volatile and non-volatile metabolites, with the effectiveness varying depending on the test phytopathogen and culture medium. Extracellular filtrates (ECFs) recovered from liquid cultures of CMU-08 under basal and induced conditions using <i>Botrytis cinerea</i> cell walls significantly inhibited their growth at a concentration of 750 µg/mL. Moreover, in detached tomato leaf assays, these ECFs reduced foliar damage caused by <i>B. cinerea</i> by 24–34%. The volatile organic compounds (VOCs) produced by CMU-08 also exhibited substantial efficacy, reducing foliar damage by up to 50% in similar tests. Despite showing no basal extracellular chitinase enzymatic activity, CMU-08 demonstrated significant induction of this activity in cultures supplemented with <i>B. cinerea</i> and <i>Fusarium</i> sp. cell walls. Four genes encoding extracellular chitinases (<i>chit33</i>, <i>chit36</i>, <i>ech42</i>, and locus 217415) showed different dynamics of transcriptional regulation during the dual-culture confrontation of strain CMU-08 with <i>B. cinerea</i> and <i>Fusarium</i> sp., varying according to the phytopathogen and the interaction stage. The CMU-08 strain shows physiological versatility and employs a variety of antagonist mechanisms toward different species of phytopathogenic microorganisms, making it a good candidate for developing a biocontrol product for field application.https://www.mdpi.com/2309-608X/10/11/758antagonism<i>Botrytis cinerea</i>detached leaf assaymycoparasitismhydrolytic enzymestranscriptional activation
spellingShingle Karla Ivonne González-Martínez
Ma. Soledad Vázquez-Garcidueñas
Alfredo Herrera-Estrella
Sylvia P. Fernández-Pavía
Rafael Salgado-Garciglia
John Larsen
Salvador Ochoa-Ascencio
Gerardo Rodríguez-Alvarado
Gerardo Vázquez-Marrufo
Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico
Journal of Fungi
antagonism
<i>Botrytis cinerea</i>
detached leaf assay
mycoparasitism
hydrolytic enzymes
transcriptional activation
title Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico
title_full Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico
title_fullStr Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico
title_full_unstemmed Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico
title_short Polyphasic Characterization of the Biocontrol Potential of a Novel Strain of <i>Trichoderma atroviride</i> Isolated from Central Mexico
title_sort polyphasic characterization of the biocontrol potential of a novel strain of i trichoderma atroviride i isolated from central mexico
topic antagonism
<i>Botrytis cinerea</i>
detached leaf assay
mycoparasitism
hydrolytic enzymes
transcriptional activation
url https://www.mdpi.com/2309-608X/10/11/758
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