How PPAR-alpha mediated inflammation may affect the pathophysiology of chronic kidney disease

Chronic kidney disease (CKD) is a major risk factor for death in adults. Inflammation plays a role in the pathogenesis of CKD, but the mechanisms are poorly understood. Peroxisome proliferator-activated receptor alpha (PPAR-α) is a nuclear receptor and one of the three members (PPARα, PPARβ/δ, and P...

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Bibliographic Details
Main Authors: Sepiso K. Masenga, Selam Desta, Mark Hatcher, Annet Kirabo, Dexter L. Lee
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Physiology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2665944124000178
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