Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review
The burden of disease and death attributable to environmental pollution is a growing public health challenge worldwide, particularly in developing countries. While the adverse effects of environmental pollution on oral health have garnered increasing attention, a comprehensive and systematic assessm...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1482991/full |
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| author | Li Zhu Mengchen Tang Yinyin Cai Yinyin Cai Panpan Wang Panpan Wang |
| author_facet | Li Zhu Mengchen Tang Yinyin Cai Yinyin Cai Panpan Wang Panpan Wang |
| author_sort | Li Zhu |
| collection | DOAJ |
| description | The burden of disease and death attributable to environmental pollution is a growing public health challenge worldwide, particularly in developing countries. While the adverse effects of environmental pollution on oral health have garnered increasing attention, a comprehensive and systematic assessment remains lacking. This article delves into the intricate relationship between environmental pollution and oral health, highlighting significant impacts on various aspects such as dental caries, periodontal diseases, oral facial clefts, cancer, as well as other oral diseases. Our results suggested that secondhand smoke, particulate matters (PM) and heavy metals are the most important risk factors affecting oral health. Additional contributors, such as radiation pollutants, electronic cigarette, phthalates, gaseous air pollutants, pesticides, solvents, wood dust, formaldehyde and excessive fluoride were investigated, though evidence for their impacts remains limited and often inconclusive. The review also explores potential mechanisms underlying these impacts, including microorganism, inflammation, oxidative stress, genetic influences, and toxicant exposures from heavy metals and other pollutants. For instance, PM2.5 may contribute to dental caries by disrupting oral pH balance and absorbing heavy metals such as lead and cadmium which have been considered as caries promoting elements. It is also associated with adverse inflammatory responses and tissue damage in periodontal tissues by causing oxidative stress, potentially leading to periodontitis. Drawing on current evidence, it provides a comprehensive analysis of these associations, offering critical insights to guide the development of preventive strategies and public health interventions. The findings highlight the pressing need for future research to validate the causal links between environmental pollution and oral diseases and to unravel the underlying biological mechanisms. Ultimately, greater attention must be directed toward addressing the relationship between environmental pollution and oral diseases, with a focus on pollution control and the reduction of preventable environmental risks to safeguard oral health on a broader scale. |
| format | Article |
| id | doaj-art-1289c28c577f4287b8d046525a41d550 |
| institution | Kabale University |
| issn | 2296-2565 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj-art-1289c28c577f4287b8d046525a41d5502025-01-06T06:59:28ZengFrontiers Media S.A.Frontiers in Public Health2296-25652025-01-011210.3389/fpubh.2024.14829911482991Association between exposure to environmental pollutants and increased oral health risks, a comprehensive reviewLi Zhu0Mengchen Tang1Yinyin Cai2Yinyin Cai3Panpan Wang4Panpan Wang5Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, ChinaGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, ChinaInstitute of Atmospheric Environmental Economics, Nanjing University of Information Science and Technology, Nanjing, ChinaShenzhen Institute of Meteorological Innovation, Shenzhen, ChinaGuangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, ChinaDepartment of Periodontology, Guanghua School and Hospital of Stomatology, Sun Yat-sen University, Guangzhou, ChinaThe burden of disease and death attributable to environmental pollution is a growing public health challenge worldwide, particularly in developing countries. While the adverse effects of environmental pollution on oral health have garnered increasing attention, a comprehensive and systematic assessment remains lacking. This article delves into the intricate relationship between environmental pollution and oral health, highlighting significant impacts on various aspects such as dental caries, periodontal diseases, oral facial clefts, cancer, as well as other oral diseases. Our results suggested that secondhand smoke, particulate matters (PM) and heavy metals are the most important risk factors affecting oral health. Additional contributors, such as radiation pollutants, electronic cigarette, phthalates, gaseous air pollutants, pesticides, solvents, wood dust, formaldehyde and excessive fluoride were investigated, though evidence for their impacts remains limited and often inconclusive. The review also explores potential mechanisms underlying these impacts, including microorganism, inflammation, oxidative stress, genetic influences, and toxicant exposures from heavy metals and other pollutants. For instance, PM2.5 may contribute to dental caries by disrupting oral pH balance and absorbing heavy metals such as lead and cadmium which have been considered as caries promoting elements. It is also associated with adverse inflammatory responses and tissue damage in periodontal tissues by causing oxidative stress, potentially leading to periodontitis. Drawing on current evidence, it provides a comprehensive analysis of these associations, offering critical insights to guide the development of preventive strategies and public health interventions. The findings highlight the pressing need for future research to validate the causal links between environmental pollution and oral diseases and to unravel the underlying biological mechanisms. Ultimately, greater attention must be directed toward addressing the relationship between environmental pollution and oral diseases, with a focus on pollution control and the reduction of preventable environmental risks to safeguard oral health on a broader scale.https://www.frontiersin.org/articles/10.3389/fpubh.2024.1482991/fulloral diseasesenvironmental pollutioncontaminantair pollutionchemical pollutionheavy metals |
| spellingShingle | Li Zhu Mengchen Tang Yinyin Cai Yinyin Cai Panpan Wang Panpan Wang Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review Frontiers in Public Health oral diseases environmental pollution contaminant air pollution chemical pollution heavy metals |
| title | Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review |
| title_full | Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review |
| title_fullStr | Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review |
| title_full_unstemmed | Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review |
| title_short | Association between exposure to environmental pollutants and increased oral health risks, a comprehensive review |
| title_sort | association between exposure to environmental pollutants and increased oral health risks a comprehensive review |
| topic | oral diseases environmental pollution contaminant air pollution chemical pollution heavy metals |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2024.1482991/full |
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