Cell free supernatants of Bifidobacterium adolescentis and Bifidobacterium longum suppress the tumor growth in colorectal cancer organoid model

Cell free supernatants of Bifidobacterium adolescentis and Bifidobacterium longum suppress the tumor growth in colorectal cancer organoid model

Abstract The probiotic gut microbiome and its metabolites are pivotal in regulating host metabolism, inflammation, and immunity. Host genetics, colonization at birth, the host lifestyle, and exposure to diseases and drugs determine microbial composition. Dysbiosis and disruption of homeostasis in th...

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Bibliographic Details
Main Authors: Min Jung Kim, Myoung-Hyun Song, Yo-Sep Ji, Ji Won Park, Young-Kyoung Shin, Soon-Chan Kim, Gihyeon Kim, Beomki Cho, Hansoo Park, Ja-Lok Ku, Seung-Yong Jeong
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Microbiome
Bifidobacterium
Organoid
Metabolite
Online Access:https://doi.org/10.1038/s41598-024-83048-5
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