<italic>Hedyotis Diffusa</italic> Willd Increase Drugs Accumulation by Regulating Hedgehog Pathway in Drug Resistant Colorectal Cancer Cells

<italic>Hedyotis Diffusa</italic> Willd Increase Drugs Accumulation by Regulating Hedgehog Pathway in Drug Resistant Colorectal Cancer Cells

Objective:To explore the effect and underlying mechanism of <italic>Hedyotis diffusa</italic> Willd (HDW) on drug efflux and regulation of Hedgehog (HH) signaling pathway in human colorectal cancer HCT-8/5-FU cells.Methods:HCT-8/5-FU Cells were treated with different concentrations of et...

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Bibliographic Details
Main Authors: Yiyi JIN, Qiongyu LI, Zijun LAI, Zhaokun YAN, Jianyu FENG, Jiumao LIN
Format: Article
Language:English
Published: Editorial Office of Rehabilitation Medicine 2016-06-01
Series:康复学报
Subjects:
colorectal cancer
<italic>Hedyotis Diffusa</italic> Willd
drug resistance
Hedgehog signaling pathway
5-Fluorouracil
adriamycin
Online Access:http://kfxb.publish.founderss.cn/thesisDetails#10.3724/SP.J.1329.2016.03034
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