LncRNA-HMG incites colorectal cancer cells to chemoresistance via repressing p53-mediated ferroptosis

LncRNA-HMG incites colorectal cancer cells to chemoresistance via repressing p53-mediated ferroptosis

Upon chemotherapy, excessive reactive oxygen species (ROS) often lead to the production of massive lipid peroxides in cancer cells and induce cell death, namely ferroptosis. The elimination of ROS is pivotal for tumor cells to escape from ferroptosis and acquire drug resistance. Nevertheless, the pr...

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Bibliographic Details
Main Authors: Zechang Xin, Chenyu Hu, Chunfeng Zhang, Ming Liu, Juan Li, Xiaoyan Sun, Yang Hu, Xiaofeng Liu, Kun Wang
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Redox Biology
Subjects:
LncRNA-HMG
Colorectal cancer
Chemoresistance
Ferroptosis
p53
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724003409
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