Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes
Abstract Maintaining a diverse and balanced sow milk microbiome is essential to piglet development. Thus, this study aimed to examine the effects of probiotic Bacillus licheniformis supplementation on the microbiome composition of sow colostrum and milk, and to review associated health findings in p...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-84573-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841559637227208704 |
|---|---|
| author | Rungdawan Wongsamart Naraporn Somboonna Thanya Cheibchalard Piriya Klankeo Jakavat Ruampatana Morakot Nuntapaitoon |
| author_facet | Rungdawan Wongsamart Naraporn Somboonna Thanya Cheibchalard Piriya Klankeo Jakavat Ruampatana Morakot Nuntapaitoon |
| author_sort | Rungdawan Wongsamart |
| collection | DOAJ |
| description | Abstract Maintaining a diverse and balanced sow milk microbiome is essential to piglet development. Thus, this study aimed to examine the effects of probiotic Bacillus licheniformis supplementation on the microbiome composition of sow colostrum and milk, and to review associated health findings in piglets. B. licheniformis DSMZ 28710 was supplemented at 10 g/day as feed additive before predicted farrowing until weaning by top dressing. Colostrum and milk samples were collected for metagenomic DNA extraction, 16s rRNA sequencing, and bioinformatics analyses for bacterial microbiota diversity. Results indicated that the supplementation increased the abundances of beneficial bacteria, such as Lactobacillus, Pediococcus, Bacteroides, and Bifidobacterium, while decreasing the abundances of pathogenic bacteria, such as Staphylococcus aureus, Enterobacteriaceae, and Campylobacter in the colostrum. The supplementation increased diversity while maintaining richness and evenness. Moreover, the rise in predicted microbial community metabolic function in membrane transport pathways provides crucial evidence showing that the supplementation is potentially beneficial to piglets, as these pathways are important for providing nutrients and immunity to offspring. This research highlights the importance of microbiome composition in sow milk and the potential of B. licheniformis supplementation as a means to improve piglet health and development. |
| format | Article |
| id | doaj-art-117b5aa6bc2e44ac89155b0ea41b58ad |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-117b5aa6bc2e44ac89155b0ea41b58ad2025-01-05T12:17:06ZengNature PortfolioScientific Reports2045-23222025-01-0115111410.1038/s41598-024-84573-zProbiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomesRungdawan Wongsamart0Naraporn Somboonna1Thanya Cheibchalard2Piriya Klankeo3Jakavat Ruampatana4Morakot Nuntapaitoon5Department of Microbiology, Faculty of Science, Chulalongkorn UniversityDepartment of Microbiology, Faculty of Science, Chulalongkorn UniversityDepartment of Microbiology, Faculty of Science, Chulalongkorn UniversityOmics Sciences and Bioinformatics Center, Faculty of Science, Chulalongkorn UniversityDepartment of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn UniversityMulti-Omics for Functional Products in Food, Cosmetics and Animals Research Unit, Chulalongkorn UniversityAbstract Maintaining a diverse and balanced sow milk microbiome is essential to piglet development. Thus, this study aimed to examine the effects of probiotic Bacillus licheniformis supplementation on the microbiome composition of sow colostrum and milk, and to review associated health findings in piglets. B. licheniformis DSMZ 28710 was supplemented at 10 g/day as feed additive before predicted farrowing until weaning by top dressing. Colostrum and milk samples were collected for metagenomic DNA extraction, 16s rRNA sequencing, and bioinformatics analyses for bacterial microbiota diversity. Results indicated that the supplementation increased the abundances of beneficial bacteria, such as Lactobacillus, Pediococcus, Bacteroides, and Bifidobacterium, while decreasing the abundances of pathogenic bacteria, such as Staphylococcus aureus, Enterobacteriaceae, and Campylobacter in the colostrum. The supplementation increased diversity while maintaining richness and evenness. Moreover, the rise in predicted microbial community metabolic function in membrane transport pathways provides crucial evidence showing that the supplementation is potentially beneficial to piglets, as these pathways are important for providing nutrients and immunity to offspring. This research highlights the importance of microbiome composition in sow milk and the potential of B. licheniformis supplementation as a means to improve piglet health and development.https://doi.org/10.1038/s41598-024-84573-zBacillus licheniformisProbioticsMicrobiomeSow milkGestation and lactation |
| spellingShingle | Rungdawan Wongsamart Naraporn Somboonna Thanya Cheibchalard Piriya Klankeo Jakavat Ruampatana Morakot Nuntapaitoon Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes Scientific Reports Bacillus licheniformis Probiotics Microbiome Sow milk Gestation and lactation |
| title | Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes |
| title_full | Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes |
| title_fullStr | Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes |
| title_full_unstemmed | Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes |
| title_short | Probiotic Bacillus licheniformis DSMZ 28710 improves sow milk microbiota and enhances piglet health outcomes |
| title_sort | probiotic bacillus licheniformis dsmz 28710 improves sow milk microbiota and enhances piglet health outcomes |
| topic | Bacillus licheniformis Probiotics Microbiome Sow milk Gestation and lactation |
| url | https://doi.org/10.1038/s41598-024-84573-z |
| work_keys_str_mv | AT rungdawanwongsamart probioticbacilluslicheniformisdsmz28710improvessowmilkmicrobiotaandenhancespiglethealthoutcomes AT narapornsomboonna probioticbacilluslicheniformisdsmz28710improvessowmilkmicrobiotaandenhancespiglethealthoutcomes AT thanyacheibchalard probioticbacilluslicheniformisdsmz28710improvessowmilkmicrobiotaandenhancespiglethealthoutcomes AT piriyaklankeo probioticbacilluslicheniformisdsmz28710improvessowmilkmicrobiotaandenhancespiglethealthoutcomes AT jakavatruampatana probioticbacilluslicheniformisdsmz28710improvessowmilkmicrobiotaandenhancespiglethealthoutcomes AT morakotnuntapaitoon probioticbacilluslicheniformisdsmz28710improvessowmilkmicrobiotaandenhancespiglethealthoutcomes |