Altered plasma levels of the SARS-CoV-2-related proteins ACE2 and TMPRSS2 in patients with Crohn’s disease

Altered plasma levels of the SARS-CoV-2-related proteins ACE2 and TMPRSS2 in patients with Crohn’s disease

Abstract The SARS-CoV-2 coronavirus infects cells through the cellular receptor angiotensin-converting enzyme 2 (ACE2), and the protease TMPRSS2 for the priming of viral spike protein. Thus, changes in these key proteins due to chronic conditions can increase risk for SARS-CoV2 infection; but signif...

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Bibliographic Details
Main Authors: Jorge Sáez-Leyva, Matthew P. Lennol, Carlos Avilés-Granados, María-Salud García-Ayllón, Ana Gutiérrez, Rubén Francés, Javier Sáez-Valero
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
ACE2
Crohn’s disease
Inflammatory bowel disease
Plasma
Biological therapy
TMPRSS2
Online Access:https://doi.org/10.1038/s41598-024-81810-3
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https://doi.org/10.1038/s41598-024-81810-3

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