Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review
Objective. To emphasize the role of apheresis in management of pancreatitis. Methods. The clinical course of a patient admitted for hypertriglyceridemia-induced pancreatitis (HTGP) complicated by multiorgan dysfunction is described, who demonstrated dramatic improvement in his clinical status after...
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| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/4017573 |
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| author | Harleen Dehal Michael Adashek |
| author_facet | Harleen Dehal Michael Adashek |
| author_sort | Harleen Dehal |
| collection | DOAJ |
| description | Objective. To emphasize the role of apheresis in management of pancreatitis. Methods. The clinical course of a patient admitted for hypertriglyceridemia-induced pancreatitis (HTGP) complicated by multiorgan dysfunction is described, who demonstrated dramatic improvement in his clinical status after total plasma exchange (TPE). In addition, the current guidelines for TPE and the alternative treatment options for HTGP are also presented. Results. A patient presenting with pancreatitis associated with severe systemic inflammatory response was admitted to our hospital with an initial triglyceride level of 1181 mg/dL. Given the patient’s worsening clinical condition, he was started on TPE with a rapid fall in his serum TG levels, in turn leading to early clinical recovery. Conclusion. Though various therapeutic options for the treatment of HTGP are described in literature, there are no set guidelines available to tackle this difficult clinical situation. TPE, albeit not very well known in this context, is one of the many therapies available. Though it leads to a rapid, precipitous fall in the TG levels and early symptom resolution, the data about the long-term morbidity as well as the effectiveness of this therapy is still lacking. |
| format | Article |
| id | doaj-art-115e00c281b84d82b2757a6aadce66f5 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-115e00c281b84d82b2757a6aadce66f52025-08-20T03:54:11ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/40175734017573Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature ReviewHarleen Dehal0Michael Adashek1Department of Internal Medicine, Sinai Hospital, Baltimore, MD, USADepartment of Internal Medicine, Sinai Hospital, Baltimore, MD, USAObjective. To emphasize the role of apheresis in management of pancreatitis. Methods. The clinical course of a patient admitted for hypertriglyceridemia-induced pancreatitis (HTGP) complicated by multiorgan dysfunction is described, who demonstrated dramatic improvement in his clinical status after total plasma exchange (TPE). In addition, the current guidelines for TPE and the alternative treatment options for HTGP are also presented. Results. A patient presenting with pancreatitis associated with severe systemic inflammatory response was admitted to our hospital with an initial triglyceride level of 1181 mg/dL. Given the patient’s worsening clinical condition, he was started on TPE with a rapid fall in his serum TG levels, in turn leading to early clinical recovery. Conclusion. Though various therapeutic options for the treatment of HTGP are described in literature, there are no set guidelines available to tackle this difficult clinical situation. TPE, albeit not very well known in this context, is one of the many therapies available. Though it leads to a rapid, precipitous fall in the TG levels and early symptom resolution, the data about the long-term morbidity as well as the effectiveness of this therapy is still lacking.http://dx.doi.org/10.1155/2018/4017573 |
| spellingShingle | Harleen Dehal Michael Adashek Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review Case Reports in Medicine |
| title | Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review |
| title_full | Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review |
| title_fullStr | Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review |
| title_full_unstemmed | Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review |
| title_short | Total Plasma Exchange in Hypertriglyceridemia-Induced Pancreatitis: Case Report and Literature Review |
| title_sort | total plasma exchange in hypertriglyceridemia induced pancreatitis case report and literature review |
| url | http://dx.doi.org/10.1155/2018/4017573 |
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