The highly rugged yet navigable regulatory landscape of the bacterial transcription factor TetR
Abstract Transcription factor binding sites (TFBSs) are important sources of evolutionary innovations. Understanding how evolution navigates the sequence space of such sites can be achieved by mapping TFBS adaptive landscapes. In such a landscape, an individual location corresponds to a TFBS bound b...
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Main Authors: | Cauã Antunes Westmann, Leander Goldbach, Andreas Wagner |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-12-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-54723-y |
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