BONE REGENERATION MATERIALS IN SUBSTANCE LOSS

Aim of the study is to evaluate and compare bone regeneration materials currently available in dentistry and to study the process of integrating these materials into oral and maxillofacial bone defects. Materials and methods The literature was electronically searched, and includes multiple subtopics...

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Main Authors: Chiriac Marta, Mușat Mihaela, Vizitiu Oana, Tibeica Andreea, Radu Ioan Alexandru, Norina Forna
Format: Article
Language:English
Published: Romanian Dental Association for Education 2024-06-01
Series:Romanian Journal of Medical and Dental Education
Subjects:
Online Access:https://journal.adre.ro/bone-regeneration-materials-in-substance-loss/
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author Chiriac Marta
Mușat Mihaela
Vizitiu Oana
Tibeica Andreea
Radu Ioan Alexandru
Norina Forna
author_facet Chiriac Marta
Mușat Mihaela
Vizitiu Oana
Tibeica Andreea
Radu Ioan Alexandru
Norina Forna
author_sort Chiriac Marta
collection DOAJ
description Aim of the study is to evaluate and compare bone regeneration materials currently available in dentistry and to study the process of integrating these materials into oral and maxillofacial bone defects. Materials and methods The literature was electronically searched, and includes multiple subtopics: guided bone regeneration, osteogenesis, implant surgery, bone defects, biomaterials, barrier membranes, the knowledge that must be implemented in the treatment. Results Materials are classified based on their biological functions. Functionalization strategies designed to overcome the negative properties, and facilitate space maintenance, osteoblast proliferation and differentiation, progenitor cell migration and differentiation, mineralization, vascularization, immunoregulation-induced osteogenesis, and anti-infective functionality. Conclusions Biomaterials used for bone regeneration are valid when the correct material is used. As yet the osteogenic capacity of autogenous bone has not been equalled by biomaterials. Tissue engineering has caused great interest because of its many possibilities, although more studies are necessary in order to achieve the ambitious expectations when it comes to tissue or organ regeneration in the human body.
format Article
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institution Kabale University
issn 2393-1531
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language English
publishDate 2024-06-01
publisher Romanian Dental Association for Education
record_format Article
series Romanian Journal of Medical and Dental Education
spelling doaj-art-112bcce7750147438ad6be9f843283692025-01-08T07:49:23ZengRomanian Dental Association for EducationRomanian Journal of Medical and Dental Education2393-15312393-11082024-06-011333240BONE REGENERATION MATERIALS IN SUBSTANCE LOSSChiriac Marta0Mușat Mihaela1Vizitiu Oana2Tibeica Andreea3Radu Ioan Alexandru4Norina Forna5“Gr. T. Popa" U.M.Ph. - Iași, Romania, Faculty of Dentistry, Department of Implantology, Removable Dentures, Dentures Technology“Gr. T. Popa" U.M.Ph. - Iași, Romania, Faculty of Dentistry, Department of Implantology, Removable Dentures, Dentures Technology“Gr. T. Popa" U.M.Ph. - Iași, Romania, Faculty of Dentistry, Department of Implantology, Removable Dentures, Dentures Technology“Gr. T. Popa" U.M.Ph. - Iași, Romania, Faculty of Dentistry, Department of Implantology, Removable Dentures, Dentures Technology“Gr. T. Popa" U.M.Ph. - Iași, Romania, Faculty of Dentistry, Department of Implantology, Removable Dentures, Dentures Technology“Gr. T. Popa" U.M.Ph. - Iași, Romania, Faculty of Dentistry, Department of Implantology, Removable Dentures, Dentures TechnologyAim of the study is to evaluate and compare bone regeneration materials currently available in dentistry and to study the process of integrating these materials into oral and maxillofacial bone defects. Materials and methods The literature was electronically searched, and includes multiple subtopics: guided bone regeneration, osteogenesis, implant surgery, bone defects, biomaterials, barrier membranes, the knowledge that must be implemented in the treatment. Results Materials are classified based on their biological functions. Functionalization strategies designed to overcome the negative properties, and facilitate space maintenance, osteoblast proliferation and differentiation, progenitor cell migration and differentiation, mineralization, vascularization, immunoregulation-induced osteogenesis, and anti-infective functionality. Conclusions Biomaterials used for bone regeneration are valid when the correct material is used. As yet the osteogenic capacity of autogenous bone has not been equalled by biomaterials. Tissue engineering has caused great interest because of its many possibilities, although more studies are necessary in order to achieve the ambitious expectations when it comes to tissue or organ regeneration in the human body.https://journal.adre.ro/bone-regeneration-materials-in-substance-loss/guided bone regeneration (gbr)osteogenesisbiofunctional materials
spellingShingle Chiriac Marta
Mușat Mihaela
Vizitiu Oana
Tibeica Andreea
Radu Ioan Alexandru
Norina Forna
BONE REGENERATION MATERIALS IN SUBSTANCE LOSS
Romanian Journal of Medical and Dental Education
guided bone regeneration (gbr)
osteogenesis
biofunctional materials
title BONE REGENERATION MATERIALS IN SUBSTANCE LOSS
title_full BONE REGENERATION MATERIALS IN SUBSTANCE LOSS
title_fullStr BONE REGENERATION MATERIALS IN SUBSTANCE LOSS
title_full_unstemmed BONE REGENERATION MATERIALS IN SUBSTANCE LOSS
title_short BONE REGENERATION MATERIALS IN SUBSTANCE LOSS
title_sort bone regeneration materials in substance loss
topic guided bone regeneration (gbr)
osteogenesis
biofunctional materials
url https://journal.adre.ro/bone-regeneration-materials-in-substance-loss/
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AT musatmihaela boneregenerationmaterialsinsubstanceloss
AT vizitiuoana boneregenerationmaterialsinsubstanceloss
AT tibeicaandreea boneregenerationmaterialsinsubstanceloss
AT raduioanalexandru boneregenerationmaterialsinsubstanceloss
AT norinaforna boneregenerationmaterialsinsubstanceloss