Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone
In this study, two isomeric cathinone derivatives, <i>N</i>-butyl-norbutylone and <i>N</i>-ethylhexylone, seized on the illicit drug market in Poland, were described and characterized by various instrumental analytical methods. The compounds were characterized by electrospray...
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2025-05-01
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| Series: | Molecules |
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| author | Marcin Rojkiewicz Piotr Kuś Josef Jampilek Andrzej Bąk Violetta Kozik |
| author_facet | Marcin Rojkiewicz Piotr Kuś Josef Jampilek Andrzej Bąk Violetta Kozik |
| author_sort | Marcin Rojkiewicz |
| collection | DOAJ |
| description | In this study, two isomeric cathinone derivatives, <i>N</i>-butyl-norbutylone and <i>N</i>-ethylhexylone, seized on the illicit drug market in Poland, were described and characterized by various instrumental analytical methods. The compounds were characterized by electrospray ionization mass spectrometry, high-resolution mass spectrometry, gas chromatography–mass spectrometry, and nuclear magnetic resonance spectroscopy. The two investigated compounds were confirmed as 1-(2<i>H</i>-1,3-benzodioxol-5-yl)-2-(butylamino)butan-1-one and 1-(2<i>H</i>-1,3-benzodioxol-5-yl)-2-(ethylamino)hexane-1-one, both of which were cathinone derivatives available on the new psychoactive substances (NPS) market. The obtained analytical data should be useful for forensic and toxicological purposes for quick and reliable compound identification. |
| format | Article |
| id | doaj-art-10ca0147f8fc42c7be502e88e02c3787 |
| institution | Kabale University |
| issn | 1420-3049 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj-art-10ca0147f8fc42c7be502e88e02c37872025-08-20T03:47:58ZengMDPI AGMolecules1420-30492025-05-013010218210.3390/molecules30102182Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-EthylhexyloneMarcin Rojkiewicz0Piotr Kuś1Josef Jampilek2Andrzej Bąk3Violetta Kozik4Institute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, PolandInstitute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, PolandInstitute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, PolandInstitute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, PolandInstitute of Chemistry, University of Silesia, 9 Szkolna Street, 40-006 Katowice, PolandIn this study, two isomeric cathinone derivatives, <i>N</i>-butyl-norbutylone and <i>N</i>-ethylhexylone, seized on the illicit drug market in Poland, were described and characterized by various instrumental analytical methods. The compounds were characterized by electrospray ionization mass spectrometry, high-resolution mass spectrometry, gas chromatography–mass spectrometry, and nuclear magnetic resonance spectroscopy. The two investigated compounds were confirmed as 1-(2<i>H</i>-1,3-benzodioxol-5-yl)-2-(butylamino)butan-1-one and 1-(2<i>H</i>-1,3-benzodioxol-5-yl)-2-(ethylamino)hexane-1-one, both of which were cathinone derivatives available on the new psychoactive substances (NPS) market. The obtained analytical data should be useful for forensic and toxicological purposes for quick and reliable compound identification.https://www.mdpi.com/1420-3049/30/10/2182new psychoactive substances<i>N</i>-butyl-norbutylone<i>N</i>-ethylhexylonemass spectrometryNMR spectroscopy |
| spellingShingle | Marcin Rojkiewicz Piotr Kuś Josef Jampilek Andrzej Bąk Violetta Kozik Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone Molecules new psychoactive substances <i>N</i>-butyl-norbutylone <i>N</i>-ethylhexylone mass spectrometry NMR spectroscopy |
| title | Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone |
| title_full | Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone |
| title_fullStr | Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone |
| title_full_unstemmed | Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone |
| title_short | Spectroscopic and Chromatographic Characterization of Two Isomeric Cathinone Derivatives: <i>N</i>-Butyl-Norbutylone and <i>N</i>-Ethylhexylone |
| title_sort | spectroscopic and chromatographic characterization of two isomeric cathinone derivatives i n i butyl norbutylone and i n i ethylhexylone |
| topic | new psychoactive substances <i>N</i>-butyl-norbutylone <i>N</i>-ethylhexylone mass spectrometry NMR spectroscopy |
| url | https://www.mdpi.com/1420-3049/30/10/2182 |
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