Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

Abstract DNA methylation is mediated by DNA methyltransferases (DNMTs), and the stability of their activity is essential for cellular fate. DNMT1 is considered one of the most promising targets for research. However, current detection techniques are limited in accurately quantifying its activity in...

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Bibliographic Details
Main Authors:	Yingran Wang, Guozhi Zhang, Zhizhao Zhang, Mengsi Zhang, Jiao Chen, Ke Wang, Lu Liu, Jing Bao, Ming Chen, Xiaowei Qi, Mingxuan Gao
Format:	Article
Language:	English
Published:	Wiley 2025-08-01
Series:	Advanced Science
Subjects:	breast cancer modularized tandem reaction neoadjuvant therapy response prediction plasma DNMT1 tumor burden assessment
Online Access:	https://doi.org/10.1002/advs.202501064
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