Giant nodular hidradenoma of the thigh: a case report highlighting cytological pitfalls
Abstract Nodular hidradenoma is a rare eccrine adnexal tumour that can arise in various locations, typically presenting as a solitary, slow-growing, well-circumscribed, firm, and non-tender dermal lesion. It may show discolouration, ulceration, or serous discharge, mimicking metastatic tumours, carc...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Surgical and Experimental Pathology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42047-025-00195-3 |
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| Summary: | Abstract Nodular hidradenoma is a rare eccrine adnexal tumour that can arise in various locations, typically presenting as a solitary, slow-growing, well-circumscribed, firm, and non-tender dermal lesion. It may show discolouration, ulceration, or serous discharge, mimicking metastatic tumours, carcinoma, or sarcoma. Due to its atypical presentation and lack of definitive radiological criteria, histopathology is the gold standard for diagnosis. While its subcutaneous location makes it suitable for fine needle aspiration cytology (FNAC), this technique is rarely used for small lesions, leading to limited cytomorphological data. FNAC is a cost-effective, quick, and simple tool, particularly useful in complex cases for preoperative diagnosis. Accurate identification is essential to avoid unnecessary radical treatment. This case report highlights the importance of considering nodular hidradenoma as a differential diagnosis when evaluating FNAC samples from nodular lesions in the subcutaneous region, regardless of their size or location. |
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| ISSN: | 2520-8454 |