Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum
<b>Aim:</b> The aim of this study was to determine the activity of superoxide dismutase (SOD) and total antioxidant status (TAS) of ovarian granulosa cells of hens cultured in vitro after lead (Pb) and molybdenum (Mo) administrations.<p> <b>Material and Methods:</b> Ova...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
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| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=972 |
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| author | Marcela Capcarova Adriana Kolesarova Alexander V. Sirotkin |
| author_facet | Marcela Capcarova Adriana Kolesarova Alexander V. Sirotkin |
| author_sort | Marcela Capcarova |
| collection | DOAJ |
| description | <b>Aim:</b> The aim of this study was to determine the activity of
superoxide dismutase (SOD) and total antioxidant status
(TAS) of ovarian granulosa cells of hens cultured in vitro after
lead (Pb) and molybdenum (Mo) administrations.<p>
<b>Material and Methods:</b> Ovarian granulosa cells were incubated
with lead acetate/ammonium molybdate administrations
as follows: group A (0.09/0.09 mg/mL), group B
(0.13/0.13 mg/mL), group C (0.17/0.17 mg/mL), group D
(0.33/0.33 mg/mL), group E (0.5/0.5 mg/mL) and the control
group without any additions for 18 h.<p>
<b>Results:</b> Antioxidant status of granulosa cells was dependent
on Pb and Mo doses. Higher doses of both metals
caused significant reduction of SOD activity. TAS of cells was
decreased in experimental groups.<p>
<b>Conclusion:</b> Trace elements can adversely affect animal reproductive
system and its functions, through either direct
or indirect effects on oxidative stress induction. |
| format | Article |
| id | doaj-art-1028b5a8fbf54f388cd3a06857f44be3 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-1028b5a8fbf54f388cd3a06857f44be32025-01-02T22:36:24ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953284209213972Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenumMarcela Capcarova0Adriana Kolesarova1Alexander V. Sirotkin2Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr A. HlinkuDepartment of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr A. HlinkuDepartment of Genetics and Reproduction, Animal Production Research Centre Nitra, Hlohovecka, Nitra, Slovak Republic<b>Aim:</b> The aim of this study was to determine the activity of superoxide dismutase (SOD) and total antioxidant status (TAS) of ovarian granulosa cells of hens cultured in vitro after lead (Pb) and molybdenum (Mo) administrations.<p> <b>Material and Methods:</b> Ovarian granulosa cells were incubated with lead acetate/ammonium molybdate administrations as follows: group A (0.09/0.09 mg/mL), group B (0.13/0.13 mg/mL), group C (0.17/0.17 mg/mL), group D (0.33/0.33 mg/mL), group E (0.5/0.5 mg/mL) and the control group without any additions for 18 h.<p> <b>Results:</b> Antioxidant status of granulosa cells was dependent on Pb and Mo doses. Higher doses of both metals caused significant reduction of SOD activity. TAS of cells was decreased in experimental groups.<p> <b>Conclusion:</b> Trace elements can adversely affect animal reproductive system and its functions, through either direct or indirect effects on oxidative stress induction.http://eurasianjvetsci.org/pdf.php3?id=972granulosa cellsleadmolybdenumsodtotal antioxidant status |
| spellingShingle | Marcela Capcarova Adriana Kolesarova Alexander V. Sirotkin Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum Eurasian Journal of Veterinary Sciences granulosa cells lead molybdenum sod total antioxidant status |
| title | Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum |
| title_full | Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum |
| title_fullStr | Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum |
| title_full_unstemmed | Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum |
| title_short | Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum |
| title_sort | superoxide dismutase and antioxidant status of hens granulosa cells exposed to lead and molybdenum |
| topic | granulosa cells lead molybdenum sod total antioxidant status |
| url | http://eurasianjvetsci.org/pdf.php3?id=972 |
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