Superoxide dismutase and antioxidant status of hens' granulosa cells exposed to lead and molybdenum
<b>Aim:</b> The aim of this study was to determine the activity of superoxide dismutase (SOD) and total antioxidant status (TAS) of ovarian granulosa cells of hens cultured in vitro after lead (Pb) and molybdenum (Mo) administrations.<p> <b>Material and Methods:</b> Ova...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=972 |
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| Summary: | <b>Aim:</b> The aim of this study was to determine the activity of
superoxide dismutase (SOD) and total antioxidant status
(TAS) of ovarian granulosa cells of hens cultured in vitro after
lead (Pb) and molybdenum (Mo) administrations.<p>
<b>Material and Methods:</b> Ovarian granulosa cells were incubated
with lead acetate/ammonium molybdate administrations
as follows: group A (0.09/0.09 mg/mL), group B
(0.13/0.13 mg/mL), group C (0.17/0.17 mg/mL), group D
(0.33/0.33 mg/mL), group E (0.5/0.5 mg/mL) and the control
group without any additions for 18 h.<p>
<b>Results:</b> Antioxidant status of granulosa cells was dependent
on Pb and Mo doses. Higher doses of both metals
caused significant reduction of SOD activity. TAS of cells was
decreased in experimental groups.<p>
<b>Conclusion:</b> Trace elements can adversely affect animal reproductive
system and its functions, through either direct
or indirect effects on oxidative stress induction. |
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| ISSN: | 1309-6958 2146-1953 |