Xanthogranulomatous Inflammation of Colon: A Case Report
Xanthogranulomatous Inflammation (XGI) is a rare pathological condition that can affect various organs, such as lungs, endometrium, vagina, fallopian tube, ovary, testis, stomach, colon, appendix and pancreas. However, most common sites being kidney and gallbladder. XGI has been infrequently documen...
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| Language: | English |
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JCDR Research and Publications Private Limited
2024-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/20442/72629_CE[Ra1]new_F(SHU)_QC(SD_SS)_PF1_(RI_OM)_PFA(IS)_PB(RI_IS)_PN(IS).pdf |
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| author | Ramya Lakshminarayanan Priyathersini Nagarajan Divya Madhala N Nitesh |
| author_facet | Ramya Lakshminarayanan Priyathersini Nagarajan Divya Madhala N Nitesh |
| author_sort | Ramya Lakshminarayanan |
| collection | DOAJ |
| description | Xanthogranulomatous Inflammation (XGI) is a rare pathological condition that can affect various organs, such as lungs, endometrium, vagina, fallopian tube, ovary, testis, stomach, colon, appendix and pancreas. However, most common sites being kidney and gallbladder. XGI has been infrequently documented in the colon, particularly with stricture formation. The current case reports presents the case of a 54-year-old female admitted with a 20 day history of abdominal pain, who was clinically diagnosed with an inflammatory lesion causing luminal narrowing. Colonoscopy revealed a sigmoid polyp, which, upon biopsy, showed acute inflammatory granulation tissue with ulceration. A sigmoidectomy was performed due to persistent pain, revealing a sigmoid colon stricture characterised microscopically by foamy histiocytes amidst dense inflammatory infiltrate and multinucleate giant cell. The present case underscores the importance of considering XGI in patients presenting with bowel mass, obstruction, or stricture. |
| format | Article |
| id | doaj-art-100c789303804fe2a392bc60cf3dd408 |
| institution | Kabale University |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-100c789303804fe2a392bc60cf3dd4082025-01-04T11:44:12ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2024-12-011812121410.7860/JCDR/2024/72629.20442Xanthogranulomatous Inflammation of Colon: A Case ReportRamya Lakshminarayanan0Priyathersini Nagarajan1Divya Madhala2N Nitesh3Postgraduate, Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, IndiaAssociate Professor, Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.Senior Resident, Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.Associate Professor, Department of General Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, IndiaXanthogranulomatous Inflammation (XGI) is a rare pathological condition that can affect various organs, such as lungs, endometrium, vagina, fallopian tube, ovary, testis, stomach, colon, appendix and pancreas. However, most common sites being kidney and gallbladder. XGI has been infrequently documented in the colon, particularly with stricture formation. The current case reports presents the case of a 54-year-old female admitted with a 20 day history of abdominal pain, who was clinically diagnosed with an inflammatory lesion causing luminal narrowing. Colonoscopy revealed a sigmoid polyp, which, upon biopsy, showed acute inflammatory granulation tissue with ulceration. A sigmoidectomy was performed due to persistent pain, revealing a sigmoid colon stricture characterised microscopically by foamy histiocytes amidst dense inflammatory infiltrate and multinucleate giant cell. The present case underscores the importance of considering XGI in patients presenting with bowel mass, obstruction, or stricture.https://www.jcdr.net/articles/PDF/20442/72629_CE[Ra1]new_F(SHU)_QC(SD_SS)_PF1_(RI_OM)_PFA(IS)_PB(RI_IS)_PN(IS).pdffoamy macrophageshistiocytesinflammatory infiltratemalignancystricture |
| spellingShingle | Ramya Lakshminarayanan Priyathersini Nagarajan Divya Madhala N Nitesh Xanthogranulomatous Inflammation of Colon: A Case Report Journal of Clinical and Diagnostic Research foamy macrophages histiocytes inflammatory infiltrate malignancy stricture |
| title | Xanthogranulomatous Inflammation of Colon: A Case Report |
| title_full | Xanthogranulomatous Inflammation of Colon: A Case Report |
| title_fullStr | Xanthogranulomatous Inflammation of Colon: A Case Report |
| title_full_unstemmed | Xanthogranulomatous Inflammation of Colon: A Case Report |
| title_short | Xanthogranulomatous Inflammation of Colon: A Case Report |
| title_sort | xanthogranulomatous inflammation of colon a case report |
| topic | foamy macrophages histiocytes inflammatory infiltrate malignancy stricture |
| url | https://www.jcdr.net/articles/PDF/20442/72629_CE[Ra1]new_F(SHU)_QC(SD_SS)_PF1_(RI_OM)_PFA(IS)_PB(RI_IS)_PN(IS).pdf |
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