Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research
Cell culture banks play a crucial role in advancing biomedical research by providing standardized, reproducible biological materials essential for various applications, from drug development to regenerative medicine. This opinion article presents a comprehensive overview of cell culture banks, explo...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-11-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/13/22/1861 |
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| author | Sabine Weiskirchen Antonio M. Monteiro Radovan Borojevic Ralf Weiskirchen |
| author_facet | Sabine Weiskirchen Antonio M. Monteiro Radovan Borojevic Ralf Weiskirchen |
| author_sort | Sabine Weiskirchen |
| collection | DOAJ |
| description | Cell culture banks play a crucial role in advancing biomedical research by providing standardized, reproducible biological materials essential for various applications, from drug development to regenerative medicine. This opinion article presents a comprehensive overview of cell culture banks, exploring their establishment, maintenance, and characterization processes. The significance of ethical considerations and regulatory frameworks governing the use of cell lines is discussed, emphasizing the importance of quality control and validation in ensuring the integrity of research outcomes. Additionally, the diverse types of cell culture banks—primary cells, immortalized cell lines, and stem cells—and their specific contributions to different fields such as cancer research, virology, and tissue engineering are examined. The impact of technological advancements on cell banking practices is also highlighted, including automation and biobanking software that enhance efficiency and data management. Furthermore, challenges faced by researchers in accessing high-quality cell lines are addressed, along with proposed strategies for improving collaboration between academic institutions and commercial entities. By unlocking the potential of cell culture banks through these discussions, this article aims to underline their indispensable role in driving innovation within biomedical research and fostering future discoveries that could lead to significant therapeutic breakthroughs. |
| format | Article |
| id | doaj-art-0fd7d0d725794df7aa4c77c003843fa5 |
| institution | Kabale University |
| issn | 2073-4409 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj-art-0fd7d0d725794df7aa4c77c003843fa52024-11-26T17:56:50ZengMDPI AGCells2073-44092024-11-011322186110.3390/cells13221861Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical ResearchSabine Weiskirchen0Antonio M. Monteiro1Radovan Borojevic2Ralf Weiskirchen3Institute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), University Hospital Aachen, D-52074 Aachen, GermanyBanco de Células do Rio de Janeiro, Rio de Janeiro 25250-020, BrazilBanco de Células do Rio de Janeiro, Rio de Janeiro 25250-020, BrazilInstitute of Molecular Pathobiochemistry, Experimental Gene Therapy and Clinical Chemistry (IFMPEGKC), University Hospital Aachen, D-52074 Aachen, GermanyCell culture banks play a crucial role in advancing biomedical research by providing standardized, reproducible biological materials essential for various applications, from drug development to regenerative medicine. This opinion article presents a comprehensive overview of cell culture banks, exploring their establishment, maintenance, and characterization processes. The significance of ethical considerations and regulatory frameworks governing the use of cell lines is discussed, emphasizing the importance of quality control and validation in ensuring the integrity of research outcomes. Additionally, the diverse types of cell culture banks—primary cells, immortalized cell lines, and stem cells—and their specific contributions to different fields such as cancer research, virology, and tissue engineering are examined. The impact of technological advancements on cell banking practices is also highlighted, including automation and biobanking software that enhance efficiency and data management. Furthermore, challenges faced by researchers in accessing high-quality cell lines are addressed, along with proposed strategies for improving collaboration between academic institutions and commercial entities. By unlocking the potential of cell culture banks through these discussions, this article aims to underline their indispensable role in driving innovation within biomedical research and fostering future discoveries that could lead to significant therapeutic breakthroughs.https://www.mdpi.com/2073-4409/13/22/1861cell culture banksquality controlbiomedical researchbiobanking technologyICLACcell authentication |
| spellingShingle | Sabine Weiskirchen Antonio M. Monteiro Radovan Borojevic Ralf Weiskirchen Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research Cells cell culture banks quality control biomedical research biobanking technology ICLAC cell authentication |
| title | Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research |
| title_full | Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research |
| title_fullStr | Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research |
| title_full_unstemmed | Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research |
| title_short | Unlocking Potential: A Comprehensive Overview of Cell Culture Banks and Their Impact on Biomedical Research |
| title_sort | unlocking potential a comprehensive overview of cell culture banks and their impact on biomedical research |
| topic | cell culture banks quality control biomedical research biobanking technology ICLAC cell authentication |
| url | https://www.mdpi.com/2073-4409/13/22/1861 |
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