The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate.
Although little is known about the role of the cystic fibrosis transmembrane regulator (CFTR) gene in reproductive physiology, numerous variants in this gene have been implicated in etiology of male infertility due to congenital bilateral absence of the vas deferens (CBAVD). Here, we studied the fer...
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Main Authors: | Gülüm Kosova, Joseph K Pickrell, Joanna L Kelley, Patrick F McArdle, Alan R Shuldiner, Mark Abney, Carole Ober |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-06-01
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Series: | PLoS Genetics |
Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000974&type=printable |
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