Molecular mechanisms of the viral encoded chaperone 100K in capsid folding and assembly of adenovirus

Abstract Adenovirus is an icosahedral, non-enveloped DNA virus that infects humans and other animals. The capsid of adenovirus is mainly assembled by the major capsid protein hexon. Folding and assembly of hexon require the viral encoded chaperone 100K, of which the detailed structure and chaperonin...

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Bibliographic Details
Main Authors: Haining Li, Luyuan Shao, Zhe Liu, Qi Liu, Ye Xiang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59301-4
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