TGF‐β effects on adipogenesis of 3T3‐L1 cells differ in 2D and 3D cell culture conditions

TGF‐β effects on adipogenesis of 3T3‐L1 cells differ in 2D and 3D cell culture conditions

The TGF‐β superfamily plays a pivotal role in the regulation of adipogenesis, but little is known about the potential differential role of the three isoforms of TGF‐β, TGF‐β‐1~3. To further elucidate their role, two‐dimensionally (2D) and three‐dimensionally (3D) cultured 3T3‐L1 mouse preadipocytes...

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Bibliographic Details
Main Authors: Araya Umetsu, Megumi Watanabe, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:FEBS Open Bio
Subjects:
3D culture
3T3‐L1 cell
adipogenesis
TGF‐β isoform
Online Access:https://doi.org/10.1002/2211-5463.13890
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