Brazilian kefir fraction mitigates the Alzheimer-like phenotype in Drosophila melanogaster with β-amyloid overexpression model

Brazilian kefir fraction mitigates the Alzheimer-like phenotype in Drosophila melanogaster with β-amyloid overexpression model

Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative condition and the primary form of dementia among elderly people. The amyloidogenic hypothesis is the main theory that explains this phenomenon and describes the extracellular accumulation of amyloid beta (Aβ) peptides. Model organi...

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Main Authors: Serena Mares Malta, Tamiris Sabrina Rodrigues, Matheus Henrique Silva, Alexandre Souza Marquez, Rafael Bernardes Ferreira, Fernanda Naves Araújo do Prado Mascarenhas, Renata Graciele Zanon, Lucas Matos Martins Bernardes, Letícia Leandro Batista, Murillo Néia Thomaz da Silva, Débora de Oliveira Santos, Ana Carolina Costa Santos, Ana Paula Mendes-Silva, Foued Salmen Spindola, Carlos Ueira-Vieira
Format: Article
Language:English
Published: Nature Portfolio 2024-10-01
Series:Scientific Reports
Subjects:
Alzheimer’s disease
Drosophila melanogaster
Kefir fractions
Online Access:https://doi.org/10.1038/s41598-024-76601-9
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