Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications
Introduction: Diabetic patients are susceptible to bacterial, viral and fungal infections because of various deficiencies in the immune system. Aim: To investigate a possible link between hepatitis B/C prevalence and microvascular complications as well as duration of diabetes. Material and me...
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2016-12-01
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| Series: | Gastroenterology Review |
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| Online Access: | https://www.termedia.pl/Hepatitis-B-and-C-seroprevalence-in-patients-with-diabetes-mellitus-and-its-relationship-with-microvascular-complications,41,28949,1,1.html |
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| author | Kadir Gisi Ali Cetinkaya Mesut Ozkaya Bulent Kantarceken Gokce Gisi Sedat Koroglu |
| author_facet | Kadir Gisi Ali Cetinkaya Mesut Ozkaya Bulent Kantarceken Gokce Gisi Sedat Koroglu |
| author_sort | Kadir Gisi |
| collection | DOAJ |
| description | Introduction: Diabetic patients are susceptible to bacterial, viral and fungal infections because of various deficiencies in the immune system.
Aim: To investigate a possible link between hepatitis B/C prevalence and microvascular complications as well as duration of diabetes.
Material and methods: In total 1263 diabetic patients (1149 type 2, 114 type 1) were enrolled in the study. The control group consisted of 1482 healthy blood donors who were over 40 years old. All diabetic patients were tested for HBsAg, anti-HBs and anti-HCV beside routine laboratory tests. Diabetic patients were divided into three groups according to their diabetes duration, and all of the patients were scanned for microvascular complications. Demographic data of all patients were recorded.
Results : HBsAg seropositivity was 3.7% in diabetic patients and 1.08% in the control group; this difference was statistically significant (p < 0.001). HBsAg positivity rates in type 1 and type 2 diabetics were 0.8% and 4%, respectively (p = 0.09). HCV seropositivity was 2.2% for diabetics and 0.5% for the control group; this difference was statistically significant (p 0.05). Also, no relationship was found between microvascular complications of diabetes and hepatitis B/C seropositivity.
Conclusions : Hepatitis B and C seroprevalence was found to be increased in diabetes mellitus; however, there was no relationship between hepatitis seroprevalence and the duration or microvascular complications of diabetes. |
| format | Article |
| id | doaj-art-0f02402e2ab64f618780743e5abd9ee8 |
| institution | Kabale University |
| issn | 1895-5770 1897-4317 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Gastroenterology Review |
| spelling | doaj-art-0f02402e2ab64f618780743e5abd9ee82025-01-10T14:06:14ZengTermedia Publishing HouseGastroenterology Review1895-57701897-43172016-12-0112210511010.5114/pg.2016.6474828949Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complicationsKadir GisiAli CetinkayaMesut OzkayaBulent KantarcekenGokce GisiSedat KorogluIntroduction: Diabetic patients are susceptible to bacterial, viral and fungal infections because of various deficiencies in the immune system. Aim: To investigate a possible link between hepatitis B/C prevalence and microvascular complications as well as duration of diabetes. Material and methods: In total 1263 diabetic patients (1149 type 2, 114 type 1) were enrolled in the study. The control group consisted of 1482 healthy blood donors who were over 40 years old. All diabetic patients were tested for HBsAg, anti-HBs and anti-HCV beside routine laboratory tests. Diabetic patients were divided into three groups according to their diabetes duration, and all of the patients were scanned for microvascular complications. Demographic data of all patients were recorded. Results : HBsAg seropositivity was 3.7% in diabetic patients and 1.08% in the control group; this difference was statistically significant (p < 0.001). HBsAg positivity rates in type 1 and type 2 diabetics were 0.8% and 4%, respectively (p = 0.09). HCV seropositivity was 2.2% for diabetics and 0.5% for the control group; this difference was statistically significant (p 0.05). Also, no relationship was found between microvascular complications of diabetes and hepatitis B/C seropositivity. Conclusions : Hepatitis B and C seroprevalence was found to be increased in diabetes mellitus; however, there was no relationship between hepatitis seroprevalence and the duration or microvascular complications of diabetes.https://www.termedia.pl/Hepatitis-B-and-C-seroprevalence-in-patients-with-diabetes-mellitus-and-its-relationship-with-microvascular-complications,41,28949,1,1.htmldiabetes mellitus hepatitis B prevalence hepatitis C prevalence microvascular complications |
| spellingShingle | Kadir Gisi Ali Cetinkaya Mesut Ozkaya Bulent Kantarceken Gokce Gisi Sedat Koroglu Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications Gastroenterology Review diabetes mellitus hepatitis B prevalence hepatitis C prevalence microvascular complications |
| title | Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications |
| title_full | Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications |
| title_fullStr | Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications |
| title_full_unstemmed | Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications |
| title_short | Hepatitis B and C seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications |
| title_sort | hepatitis b and c seroprevalence in patients with diabetes mellitus and its relationship with microvascular complications |
| topic | diabetes mellitus hepatitis B prevalence hepatitis C prevalence microvascular complications |
| url | https://www.termedia.pl/Hepatitis-B-and-C-seroprevalence-in-patients-with-diabetes-mellitus-and-its-relationship-with-microvascular-complications,41,28949,1,1.html |
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