Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid
Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2016/7317015 |
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| author | T. O. Aiyelabola D. A. Isabirye E. O. Akinkunmi O. A. Ogunkunle I. A. O. Ojo |
| author_facet | T. O. Aiyelabola D. A. Isabirye E. O. Akinkunmi O. A. Ogunkunle I. A. O. Ojo |
| author_sort | T. O. Aiyelabola |
| collection | DOAJ |
| description | Coordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds was determined against three Gram-positive and three Gram-negative bacteria and one fungus. The results obtained indicated that the availability of donor atoms used for coordination was a function of the pH of the solution in which the reaction was carried out. This resulted in varying geometrical structures for the complexes. The compounds exhibited a broad spectrum of activity and in some cases better activity than the standard. |
| format | Article |
| id | doaj-art-0e62a0ec1db94d95a5e15deeb6819e3f |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-0e62a0ec1db94d95a5e15deeb6819e3f2025-08-20T03:54:29ZengWileyJournal of Chemistry2090-90632090-90712016-01-01201610.1155/2016/73170157317015Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic AcidT. O. Aiyelabola0D. A. Isabirye1E. O. Akinkunmi2O. A. Ogunkunle3I. A. O. Ojo4Department of Chemistry, Obafemi Awolowo University, Ife Central, Ile-Ife 220282, Osun State, NigeriaDepartment of Chemistry NWU, Mafikeng Campus, Private Bag X2046, Mmabatho 2735, South AfricaDepartment of Pharmaceutics, Obafemi Awolowo University, Ife Central, Ile-Ife 220282, Osun State, NigeriaDepartment of Chemistry, Obafemi Awolowo University, Ife Central, Ile-Ife 220282, Osun State, NigeriaDepartment of Chemistry, Obafemi Awolowo University, Ife Central, Ile-Ife 220282, Osun State, NigeriaCoordination compounds of aspartic acid were synthesized in basic and acidic media, with metal ligand M : L stoichiometric ratio 1 : 2. The complexes were characterized using infrared, electronic and magnetic susceptibility measurements, and mass spectrometry. Antimicrobial activity of the compounds was determined against three Gram-positive and three Gram-negative bacteria and one fungus. The results obtained indicated that the availability of donor atoms used for coordination was a function of the pH of the solution in which the reaction was carried out. This resulted in varying geometrical structures for the complexes. The compounds exhibited a broad spectrum of activity and in some cases better activity than the standard.http://dx.doi.org/10.1155/2016/7317015 |
| spellingShingle | T. O. Aiyelabola D. A. Isabirye E. O. Akinkunmi O. A. Ogunkunle I. A. O. Ojo Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid Journal of Chemistry |
| title | Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid |
| title_full | Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid |
| title_fullStr | Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid |
| title_full_unstemmed | Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid |
| title_short | Synthesis, Characterization, and Antimicrobial Activities of Coordination Compounds of Aspartic Acid |
| title_sort | synthesis characterization and antimicrobial activities of coordination compounds of aspartic acid |
| url | http://dx.doi.org/10.1155/2016/7317015 |
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