Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review
IntroductionMicrobial contamination remains a vital challenge across the food production chain, particularly due to mycotoxins—secondary metabolites produced by several genera of fungi such as Aspergillus, Fusarium, Alternaria, and Penicillium. These toxins, including aflatoxins, fumonisins, ochrato...
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1502915/full |
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| author | Amanda Cristina Dias de Oliveira Sher Ali Carlos Humberto Corassin Sana Ullah Karina Nascimento Pereira James Leon Walsh Nataša Hojnik Carlos Augusto Fernandes de Oliveira |
| author_facet | Amanda Cristina Dias de Oliveira Sher Ali Carlos Humberto Corassin Sana Ullah Karina Nascimento Pereira James Leon Walsh Nataša Hojnik Carlos Augusto Fernandes de Oliveira |
| author_sort | Amanda Cristina Dias de Oliveira |
| collection | DOAJ |
| description | IntroductionMicrobial contamination remains a vital challenge across the food production chain, particularly due to mycotoxins—secondary metabolites produced by several genera of fungi such as Aspergillus, Fusarium, Alternaria, and Penicillium. These toxins, including aflatoxins, fumonisins, ochratoxins, and trichothecenes (nivalenol, deoxynivalenol, T2, HT-2). These contaminants pose severe risks to human and animal health, with their potential to produce a variety of different toxic effects. Notably, up to 50% of global cereal production is affected by mycotoxin contamination, leading to significant economic losses. Current research focuses on innovative technologies to mitigate mycotoxins, with cold atmospheric pressure plasma emerging as a promising decontamination method.MethodThis systematic review aimed at describing recent advances in the application of cold atmospheric plasma for the decontamination of toxigenic fungi and mycotoxins.Results and discussionCold atmospheric plasma offers a sustainable and cost effective solution to preserve food quality while inactivating toxigenic fungi and degrading mycotoxins. Through the generation of reactive oxygen and nitrogen species, cold plasma disrupts fungal cell integrity, hinders spore germination, and inhibits toxin biosynthesis. Additionally, cold atmospheric plasma-driven degradation of mycotoxins involves structural modifications, breaking key molecular bonds that reduce toxicity. The effectiveness of cold plasma depends on operational parameters and the specific characteristics of the treated food, with notable efficacy in degrading aflatoxin B1 and deoxynivalenol by converting them into less toxic substances and inhibiting their spores and DNA responsible for their biosynthesis. While the data demonstrates that cold atmospheric plasma has minimal impact on food composition, further research is needed to fully assess the nature of the degradation products of mycotoxins, its influence on food quality attributes and to optimize application strategies for different products. |
| format | Article |
| id | doaj-art-0de7d9fcdec64c9cb87498e14461257a |
| institution | Kabale University |
| issn | 1664-302X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Microbiology |
| spelling | doaj-art-0de7d9fcdec64c9cb87498e14461257a2025-01-03T07:47:12ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2025-01-011510.3389/fmicb.2024.15029151502915Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic reviewAmanda Cristina Dias de Oliveira0Sher Ali1Carlos Humberto Corassin2Sana Ullah3Karina Nascimento Pereira4James Leon Walsh5Nataša Hojnik6Carlos Augusto Fernandes de Oliveira7Laboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, BrazilLaboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, BrazilLaboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, BrazilLaboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, BrazilLaboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, BrazilSchool of Physics, Engineering and Technology, University of York, York, United KingdomDepartment for Gaseous Electronics, Jožef Stefan Institute, Ljubljana, SloveniaLaboratory of Food Microbiology and Mycotoxicology, Department of Food Engineering, School of Animal Science and Food Engineering, University of São Paulo, Pirassununga, BrazilIntroductionMicrobial contamination remains a vital challenge across the food production chain, particularly due to mycotoxins—secondary metabolites produced by several genera of fungi such as Aspergillus, Fusarium, Alternaria, and Penicillium. These toxins, including aflatoxins, fumonisins, ochratoxins, and trichothecenes (nivalenol, deoxynivalenol, T2, HT-2). These contaminants pose severe risks to human and animal health, with their potential to produce a variety of different toxic effects. Notably, up to 50% of global cereal production is affected by mycotoxin contamination, leading to significant economic losses. Current research focuses on innovative technologies to mitigate mycotoxins, with cold atmospheric pressure plasma emerging as a promising decontamination method.MethodThis systematic review aimed at describing recent advances in the application of cold atmospheric plasma for the decontamination of toxigenic fungi and mycotoxins.Results and discussionCold atmospheric plasma offers a sustainable and cost effective solution to preserve food quality while inactivating toxigenic fungi and degrading mycotoxins. Through the generation of reactive oxygen and nitrogen species, cold plasma disrupts fungal cell integrity, hinders spore germination, and inhibits toxin biosynthesis. Additionally, cold atmospheric plasma-driven degradation of mycotoxins involves structural modifications, breaking key molecular bonds that reduce toxicity. The effectiveness of cold plasma depends on operational parameters and the specific characteristics of the treated food, with notable efficacy in degrading aflatoxin B1 and deoxynivalenol by converting them into less toxic substances and inhibiting their spores and DNA responsible for their biosynthesis. While the data demonstrates that cold atmospheric plasma has minimal impact on food composition, further research is needed to fully assess the nature of the degradation products of mycotoxins, its influence on food quality attributes and to optimize application strategies for different products.https://www.frontiersin.org/articles/10.3389/fmicb.2024.1502915/fullCAP technologymycotoxinscontaminationfoodstuffsdetoxificationprotect |
| spellingShingle | Amanda Cristina Dias de Oliveira Sher Ali Carlos Humberto Corassin Sana Ullah Karina Nascimento Pereira James Leon Walsh Nataša Hojnik Carlos Augusto Fernandes de Oliveira Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review Frontiers in Microbiology CAP technology mycotoxins contamination foodstuffs detoxificationprotect |
| title | Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review |
| title_full | Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review |
| title_fullStr | Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review |
| title_full_unstemmed | Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review |
| title_short | Application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins: a systematic review |
| title_sort | application of cold atmospheric plasma for decontamination of toxigenic fungi and mycotoxins a systematic review |
| topic | CAP technology mycotoxins contamination foodstuffs detoxificationprotect |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2024.1502915/full |
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