FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression

FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression

IntroductionImmunosuppression is the main cause of the high mortality rate in patients with sepsis. The decrease in the number and dysfunction of CD4+ T lymphocytes is crucial to the immunosuppressed state of sepsis, in turn affecting the development and prognosis of sepsis. Autophagy has been shown...

Full description

Saved in:
Bibliographic Details
Main Authors: Guoan Xiang, Qi Li, Di Lian, Chengcheng Su, Xin Li, Shoulong Deng, Lixin Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Pharmacology
Subjects:
sepsis
miR-223
CD4+ T lymphocytes
autophagy
FOXO1
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1469286/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items