Zhongfeng Xingnao prescription alleviates injury of intracerebral hemorrhage via regulating the CaMKII/NF-κB p65/NLRP3/GSDMD signaling axis

Zhongfeng Xingnao prescription alleviates injury of intracerebral hemorrhage via regulating the CaMKII/NF-κB p65/NLRP3/GSDMD signaling axis

Background and aim: The NLRP3 inflammasome can be activated after intracerebral hemorrhage (ICH), triggering an inflammatory response in the brain. Chinese herbal medicine Zhongfeng Xingnao Prescription (ZFXN) is commonly used in China for intracerebral hemorrhage treatment. However, the underlying...

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Bibliographic Details
Main Authors: Jianyuan Yu, Huifen Zhou, Jianwen Guo, Tianhang Chen, Chongyu Shao, Zhiyong Pan, Jiehong Yang, Haitong Wan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Intracerebral hemorrhage
NLRP3 inflammasome
Ca2+/calmodulin–dependent protein kinase II
Chinese herbal medicine
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411024000245
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