The safety, pharmacokinetics and neutralizing activity of recombinant human anti-rabies monoclonal antibody NM57 injection (rhRIG, Ormutivimab) in combination with rabies vaccination in Chinese healthy adults: A phase Ib randomized, double-blind, parallel-controlled clinical study

The safety, pharmacokinetics and neutralizing activity of recombinant human anti-rabies monoclonal antibody NM57 injection (rhRIG, Ormutivimab) in combination with rabies vaccination in Chinese healthy adults: A phase Ib randomized, double-blind, parallel-controlled clinical study

Background: The combination of passive immune agents (human rabies immune globulin (HRIG) and equine rabies antiserum (ERA)) with vaccines are effective measures for preventing the onset of rabies post exposure. However, ERA and HRIG have potential risks of serum allergic reactions and blood-transmi...

Full description

Saved in:
Bibliographic Details
Main Authors: Yin Yin, Min Jia, Yufeng Li, Wei Zhao, Shuhong Chen, Peiyuan Huo, Qinghua Zhao, Lan Yu, Cha Wang, Yirui Ma, Meixia Wang, Jing Zhang
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Travel Medicine and Infectious Disease
Subjects:
Ormutivimab
rhRIG
Monoclonal antibodies
Rabies
Passive immunization
Online Access:http://www.sciencedirect.com/science/article/pii/S1477893924001091
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items